Evidence map›Paper›PMID 39035746›Full record

ArticleLeukemia research reports2024

BCR-ABL kinase domain mutations in CML patients, experience from a tertiary care center in North India.

Akhilesh S, Arunim Shah, Ashish Ashish, Nitish Kumar Singh, Manpreet Kaur, Abhay Kumar Yadav, Royana Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akhilesh SMRU Lab-Dept. of Anatomy, IMS, BHU, Varanasi, India.
Arunim ShahSCRC, SGPGIMS, Lucknow, India.
Ashish AshishMRU Lab-Dept. of Anatomy, IMS, BHU, Varanasi, India.
Nitish Kumar SinghMRU Lab-Dept. of Anatomy, IMS, BHU, Varanasi, India.
Manpreet KaurMRU Lab-Dept. of Anatomy, IMS, BHU, Varanasi, India.
Abhay Kumar YadavMRU Lab-Dept. of Anatomy, IMS, BHU, Varanasi, India.
Royana SinghMRU Lab-Dept. of Anatomy, IMS, BHU, Varanasi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic Myeloid Leukemia is characterized by the presence of the Philadelphia Chromosome (Ph) which contains the Methods: In this study, the patient resistance for the imatinib were analyzed for Results: 329 patients with CML-CP were analyzed for Conclusion: Total 20.06 % patients (66/329) show mutation in at least one of the structural motifs of BCR-ABL kinase domain, which further confer the resistance to a particular generation of TKI.

Indexed as

BCR::ABL Kinase domain mutationsChronic myeloid leukemiaImatinibPhiladelphia chromosomeSanger's sequencing

Identifiers

PMID39035746
PMCPMC11258388

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.