Evidence map›Paper›PMID 39035713›Full record

ArticleRSC advances2024

Structural analysis of peptide identified from the 2KRR domain of the nucleolin protein with a c-Myc G4 structure using biophysical and biochemical methods.

Sarvpreet Kaur, Nikita Kundu, Taniya Sharma, J Shankaraswamy, Sweta Singh, Sarika Saxena

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarvpreet KaurAmity Institute of Biotechnology, Amity University Uttar Pradesh Noida 201313 India ssaxena1@amity.edu sarikaigib@yahoo.co.in +91 120-4735600.
Nikita KunduAmity Institute of Biotechnology, Amity University Uttar Pradesh Noida 201313 India ssaxena1@amity.edu sarikaigib@yahoo.co.in +91 120-4735600.
Taniya SharmaAmity Institute of Biotechnology, Amity University Uttar Pradesh Noida 201313 India ssaxena1@amity.edu sarikaigib@yahoo.co.in +91 120-4735600.
J ShankaraswamyDepartment of Fruit Science, College of Horticulture, Mojerla, Sri Konda Laxman Telangana State Horticultural University 509382 Telangana India.
Sweta SinghInstitute of Nuclear Medicine and Allied Sciences (INMAS), DRDO Brig. S. K. Mazumdar Marg Delhi-110054 India.ORCID https://orcid.org/0000-0002-0218-3969
Sarika SaxenaAmity Institute of Biotechnology, Amity University Uttar Pradesh Noida 201313 India ssaxena1@amity.edu sarikaigib@yahoo.co.in +91 120-4735600.ORCID https://orcid.org/0000-0002-4082-5627

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the first time, the c-Myc G4 structure is reported to be stabilized by binding of the peptide (derived from the 2KRR domain of the nucleolin protein called the Nu peptide) in the loop region of the G-quadruplex structure by stacking interactions. CD results showed the formation of parallel G4 structure in the presence of 100 mM Na

Identifiers

PMID39035713
PMCPMC11258614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.