Evidence map›Paper›PMID 39035708›Full record

ArticleResearch in autism spectrum disorders2024

Correlates of Quality of Life in Autistic Individuals.

Kristen T MacKenzie, Anabelle Theodat, Kelly B Beck, Caitlin M Conner, Carla A Mazefsky, Shaun M Eack

Abstract read
In one paragraph

Article in Research in autism spectrum disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristen T MacKenzieUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-7608-1295
Anabelle TheodatUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0009-0000-8469-3657
Kelly B BeckUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0001-8094-6362
Caitlin M ConnerUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-6224-2086
Carla A MazefskyUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0001-7467-0902
Shaun M EackUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0001-6368-7004

Funding

Institutional Career Development CoreKL2TR001856 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, KRISTIN N, RUBIO, DORIS M · 2016 to 2025
$13.8M
Cognitive Enhancement Therapy for Adult Autism Spectrum DisorderR01MH106450 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EACK, SHAUN M · 2015 to 2019
$3.2M
Adapting Cognitive Enhancement Therapy for ASDR33MH085851 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MINSHEW, NANCY J · 2011 to 2013
$624k
Adapting Cognitive Enhancement Therapy for ASDR21MH085851 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MINSHEW, NANCY J · 2009 to 2010
$400k
NCATS NIH HHS KL2 TR001856NICHD NIH HHS L30 HD109969NIMH NIH HHS R01 MH106450NIMH NIH HHS R21 MH085851NIMH NIH HHS R33 MH085851
6 · The paper itself

Abstract

Background: Quality of life is an important outcome to autistic individuals. However, the correlates of quality of life in this population are not well known. The purpose of this project was to investigate the extent to which employment, depression, anxiety, and social participation were associated with quality of life in autistic individuals. We also explored potential associations between emotion dysregulation and quality of life. Method: Baseline data from two randomized control trials were used for analysis. A total of 125 autistic adolescents and adults aged 16-45 ( Results: Surprisingly, employment was not significantly associated with any quality of life domain. Greater depression severity was significantly associated with poorer quality of life across all domains. Greater social participation was associated with better quality of life, but only for individuals with lower anxiety. More severe dysphoria was associated with poorer overall quality of life and the psychological and physical health domains. Conclusions: Results suggest that mental health and emotion dysregulation are important predictors of quality of life for autistic people. They also suggest that anxiety symptoms may attenuate the beneficial effects of social participation. This study provides insight into the unique experiences of autistic individuals and highlights potential unmet need.

Indexed as

anxietyautismdepressionemploymentquality of lifesocial participation

Identifiers

PMID39035708
PMCPMC11258895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.