Evidence map›Paper›PMID 39035246›Full record

ArticleAmerican journal of medicine open2023

Screening for Hereditary Hemochromatosis in Newly Referred Diabetes Mellitus.

Michael Lockhart, Muhammad Ridhwaan Salehmohamed, Dileep Kumar, Anne Graham Cummiskey, Keat Cheah Seong, Seamus Sreenan, John McDermott

Abstract read
In one paragraph

Article in American journal of medicine open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael LockhartAcademic Department of Endocrinology and Diabetes, Connolly Hospital Blanchardstown, Dublin, Ireland.
Muhammad Ridhwaan SalehmohamedAcademic Department of Endocrinology and Diabetes, Connolly Hospital Blanchardstown, Dublin, Ireland.
Dileep KumarAcademic Department of Endocrinology and Diabetes, Connolly Hospital Blanchardstown, Dublin, Ireland.
Anne Graham CummiskeyAcademic Department of Endocrinology and Diabetes, Connolly Hospital Blanchardstown, Dublin, Ireland.
Keat Cheah SeongAcademic Department of Endocrinology and Diabetes, Connolly Hospital Blanchardstown, Dublin, Ireland.
Seamus SreenanAcademic Department of Endocrinology and Diabetes, Connolly Hospital Blanchardstown, Dublin, Ireland.
John McDermottAcademic Department of Endocrinology and Diabetes, Connolly Hospital Blanchardstown, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Hereditary hemochromatosis (HH) is the most common inherited disease in European populations. It is particularly common in people of Irish heritage, approximately 2% of whom will be at risk of iron overload as a result of human homoeostatic iron regulator protein ( Methods: Of 575 patients newly referred between March 2018 and March 2021, 556 attended for blood testing, to include fasting transferrin saturations, prior to their first clinic visit. Patients with elevated transferrin saturations were further screened for hereditary hemochromatosis (HH) with Results: Transferrin saturations were elevated in 13 of 556 patients (2.3%), 3 of whom had a preexisting diagnosis of HH. Of the remaining 10 patients, 7 had Conclusions: The prevalence of HH of 1.8% in this screened DM population is lower than the reported incidence of HH in the Irish population, suggesting a limited utility of routine screening for HH in newly referred patients with DM.

Indexed as

Diabetes mellitusHereditary hemochromatosisHFE geneTransferrin saturations

Identifiers

PMID39035246
PMCPMC11256261

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.