Evidence map›Paper›PMID 39035238›Full record

ArticleAmerican journal of medicine open2023

Is the SIRS Criteria a Good Predictor of Blood stream Infection in Cirrhosis? A Single-Center Retrospective Analysis.

Nandakumar Mohan, Samir Shah, Atif Nehvi, Edward Bley, Kevin Bryan Lo, Sarah Perloff

Abstract read
In one paragraph

Article in American journal of medicine open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nandakumar MohanDepartment of Medicine, Einstein Medical Center, Philadelphia, PA.
Samir ShahDepartment of Medicine, Einstein Medical Center, Philadelphia, PA.
Atif NehviDepartment of Medicine, Einstein Medical Center, Philadelphia, PA.
Edward BleyDepartment of Medicine, Einstein Medical Center, Philadelphia, PA.
Kevin Bryan LoDepartment of Medicine, Einstein Medical Center, Philadelphia, PA.
Sarah PerloffDivision of Infectious Diseases, Einstein Medical Center, Philadelphia, PA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cirrhosis-associated immune dysfunction (CAID) is a chronic vasodilatory state with hyperdynamic circulation and alterations in thermoregulation that may make patients more susceptible to and mask underlying infection. This study aims to determine whether SIRS criteria are an accurate tool for predicting bloodstream infection (BSI) in cirrhosis. Methods: In our retrospective chart review, study population included patients with cirrhosis that were 18 years or older. For all study patients, model for end-stage liver disease (MELD) scores and values for each SIRS variable at the time of admission and blood culture data were recorded. Univariable and multivariable logistic regression analysis was performed to identify any associations between dichotomized SIRS variables that fulfill SIRS positivity and BSI. Results: Significantly more patients without BSI met positivity criteria for WBC counts (30% vs 13% Conclusion: Our study shows that SIRS criteria are a poor predictor of BSI among patients with cirrhosis.

Indexed as

Bloodstream infectionCirrhosisCirrhosis-associated immune dysfunctionMELDSIRS

Identifiers

PMID39035238
PMCPMC11256226

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.