Evidence map›Paper›PMID 39035167›Full record

SynthesisPeerJ2024

The prognostic role of lymphocyte-to-monocyte ratio in patients with resectable pancreatic cancer: a systematic review and meta-analysis.

Haipeng Li, Shang Peng, Ran An, Nana Du, Huan Wu, Xiangcheng Zhen, Yuanzhi Gao, Zhenghong Li, Jingting Min

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haipeng LiDepartment of Mental Health, Bengbu Medical College, Bengbu, Anhui, China.
Shang PengDepartment of Basic Medicine, Bengbu Medical College, Bengbu, Anhui, China.
Ran AnDepartment of Life Science, Bengbu Medical College, Bengbu, Anhui, China.
Nana DuDepartment of Basic Medicine, Bengbu Medical College, Bengbu, Anhui, China.
Huan WuDepartment of Mental Health, Bengbu Medical College, Bengbu, Anhui, China.
Xiangcheng ZhenDepartment of Clinical Medicine, Bengbu Medical College, Bengbu, Anhui, China.
Yuanzhi GaoDepartment of Clinical Medicine, Bengbu Medical College, Bengbu, Anhui, China.
Zhenghong LiDepartment of Life Science, Bengbu Medical College, Bengbu, Anhui, China.
Jingting MinDepartment of Basic Medicine, Bengbu Medical College, Bengbu, Anhui, China.

Funding

National Innovation and Entrepreneurship ProjectPrograms from the Department of Science and Technology of Anhui Province
6 · The paper itself

Abstract

Objectives: This systematic review and meta-analysis examined whether the lymphocyte-to-monocyte ratio (LMR) can serve as an indicator for predicting the prognosis of patients with resectable pancreatic cancer. Patients and Methods: This meta-analysis was registered with PROSPERO: CRD42023461260. A systematic literature search was conducted in the PubMed, Embase, Cochrane, and Web of Science databases up to September 2023 to assess whether LMR can predict the prognosis of patients with resectable pancreatic cancer. The outcomes measured included subgroup analyses of overall survival (OS) with hazard ratios (HR) and confidence intervals of geographical region, patient population, and LMR threshold. A sensitivity analysis was also performed for OS and HR and confidence intervals were calculated for recurrence-free survival (RFS). Results: A total of 14 eligible articles, comprising 4,019 patients, were included in the comprehensive analysis. The results of this comprehensive analysis indicate that LMR is a robust predictor of OS, demonstrating strong prognostic significance (HR = 0.55, 95% CI [0.44-0.69], I Conclusion: Despite the observed heterogeneity and potential biases in the included studies, the findings of this study suggest that LMR may serve as a valuable predictor of OS in patients with resectable pancreatic cancer.

Indexed as

LymphocytesMonocytesPancreatic NeoplasmsHumansLymphocyte CountPrognosisLMRMeta-analysisPancreatic cancer

Identifiers

PMID39035167
PMCPMC11260418

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.