Evidence map›Paper›PMID 39035020›Full record

ArticleBiochemistry and biophysics reports2024

Quantitative proteome analysis of LAP1-deficient human fibroblasts: A pilot approach for predicting the signaling pathways deregulated in LAP1-associated diseases.

Cátia D Pereira, Guadalupe Espadas, Filipa Martins, Anne T Bertrand, Laurent Servais, Eduard Sabidó, Philippe Chevalier, Odete A B da Cruz E Silva, Sandra Rebelo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cátia D PereiraInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193, Aveiro, Portugal.
Guadalupe EspadasCenter for Genomics Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Filipa MartinsInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193, Aveiro, Portugal.
Anne T BertrandSorbonne Université, Inserm, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
Laurent ServaisMDUK Oxford Neuromuscular Center, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Center, Oxford, OX3 9DU, United Kingdom.
Eduard SabidóCenter for Genomics Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Philippe ChevalierUniversité Claude Bernard Lyon 1, Lyon, France.
Odete A B da Cruz E SilvaInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193, Aveiro, Portugal.
Sandra RebeloInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193, Aveiro, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lamina-associated polypeptide 1 (LAP1), a ubiquitously expressed nuclear envelope protein, appears to be essential for the maintenance of cell homeostasis. Although rare, mutations in the human LAP1-encoding

Indexed as

BioinformaticsDNA repairMass spectrometryOxidative stress responseProtein synthesisProteomicsProteostasis

Identifiers

PMID39035020
PMCPMC11260385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.