Evidence map›Paper›PMID 39034721›Full record

ArticleCurrent drug delivery2025

Ginger Extract-Loaded Chitosan Nanoparticles: Investigating their Impact on Lipid Metabolism and Obesity in a Rat Model through

Rui Gao, Qunbin Fan, Saeed Rohani

Abstract read
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In one paragraph

Article in Current drug delivery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rui GaoDepartment of Endocrinology, Xidian Group Hospital, Xi'an, 710000, China.
Qunbin FanDepartment of Nutrition, Suzhou Kowloon Hospital, Shanghai Jiao Tong University School of Medicine, Suzhou, 215028, China.
Saeed RohaniDepartment of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionObesity has become a pressing global health crisis, reaching alarming proportions and bearing significant consequences for public health on a global scale.

aimIn this research, chitosan nanoparticles were employed to encapsulate ginger extract, and the impact of this formulation on lipid metabolism and obesity was investigated using a rat model.

methods

resultsIn vitro findings affirmed the safety of the carriers and revealed their robust anti-inflammatory properties. The average particle size for ginger-loaded and ginger-free chitosan nanoparticles was measured to be 458.92 ± 139.35 nm and 466.29 ± 142.71 nm, respectively. The in vivo investigation demonstrated the dose-dependent effects of ginger extract-loaded chitosan nanoparticles, manifesting in a reduction of obesity and improvement in liver function.

conclusionThese promising results suggest that the developed nanoformulation could be considered a viable therapeutic option for individuals struggling with obesity.

Indexed as

ChitosanLipid MetabolismNanoparticlesObesityPlant ExtractsZingiber officinaleAnimalsAnti-Inflammatory AgentsCell SurvivalDiet, High-FatDisease Models, AnimalDrug CarriersDrug LiberationHumansMaleParticle SizeAnti-Inflammatory AgentsChitosanDrug Carriersginger extractPlant Extractscell viability.Chitosan nanoparticlesdrug deliveryginger extractMTT assayobesity

Identifiers

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Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.