Evidence map›Paper›PMID 39034434›Full record

ArticleEar and hearing2024

Assessing Neural Synchrony in the Cochlear Nerve to Electrical Stimulation in Children With Auditory Neuropathy Spectrum Disorder.

Shuman He, Xiuhua Chao, Yi Yuan, Jeffrey Skidmore, Kristin M Uhler

Abstract read
In one paragraph

Article in Ear and hearing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Neural Hearing Loss: Mechanisms, Diagnosis and Treatment Horizons.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuman HeDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Xiuhua ChaoDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, China.
Yi YuanDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Jeffrey SkidmoreMED-EL Corporation, Durham, North Carolina, USA.
Kristin M UhlerDepartment of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

Funding

Neural Encoding and Auditory Processing of Electrical Stimulation in Pediatric Cochlear Implant UsersR01DC017846 · NIDCD · OHIO STATE UNIVERSITY · PI HE, SHUMAN · 2019 to 2024
$2.0M
AUDITORY NEURAL FUNCTION IN IMPLANTED PATIENTS WITH USHER SYNDROMER21DC019458 · NIDCD · OHIO STATE UNIVERSITY · PI HE, SHUMAN · 2021 to 2022
$433k
NIDCD NIH HHS R01 DC017846NIDCD NIH HHS R21 DC019458
6 · The paper itself

Abstract

objectivesThis study reported phase locking values (PLVs) that quantified the trial-to-trial phase coherence of electrically evoked compound action potentials in children with auditory neuropathy spectrum disorders (ANSD) and children with Gap Junction Beta 2 (GJB2) mutations, a patient population without noticeable cochlear nerve damage.

designPLVs were measured at three electrode locations in 11 children with ANSD and 11 children with GJB2 mutations. Smaller PLVs indicated poorer neural synchrony. A linear mixed-effects model was used to compare PLVs measured at different electrode locations between participant groups.

resultsAfter controlling for the stimulation level effect, children with ANSD had smaller PLVs than children with GJB2 mutations at all three electrode locations.

conclusionsCochlear-implanted children with ANSD show poorer peripheral neural synchrony than children with GJB2 mutations.

Identifiers

PMID39034434
PMCPMC11751731

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.