Evidence map›Paper›PMID 39033533›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Natural Products from Herbal Medicine Self-Assemble into Advanced Bioactive Materials.

Xiaohang Guo, Weikang Luo, Lingyu Wu, Lianglin Zhang, Yuxuan Chen, Teng Li, Haigang Li, Wei Zhang, Yawei Liu, Jun Zheng and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Self-assembled supramolecular nanoparticles ofActa pharmaceutica Sinica. B · 2026
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaohang GuoSchool of Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China.
Weikang LuoInstitute of Integrative Medicine, Department of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Lingyu WuCollege of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China.
Lianglin ZhangInstitute of Integrative Medicine, Department of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Yuxuan ChenBeijing Normal University-Hong Kong Baptist University United International College, Zhuhai, 519087, China.
Teng LiInstitute of Integrative Medicine, Department of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Haigang LiHunan key laboratory of the research and development of novel pharmaceutical preparations, Changsha Medical University, Changsha, 410219, China.
Wei ZhangCollege of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China.
Yawei LiuSchool of Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China.
Jun ZhengInstitute of Integrative Medicine, Department of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Yang WangInstitute of Integrative Medicine, Department of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.ORCID 0000-0003-0447-3107

Funding

National Natural Science Foundation of China 82274371Natural Science Foundation of Hunan Province 2023JJ30944Postdoctoral Fellowship Program of CPS GZB20230881
6 · The paper itself

Abstract

Novel biomaterials are becoming more crucial in treating human diseases. However, many materials require complex artificial modifications and synthesis, leading to potential difficulties in preparation, side effects, and clinical translation. Recently, significant progress has been achieved in terms of direct self-assembly of natural products from herbal medicine (NPHM), an important source for novel medications, resulting in a wide range of bioactive supramolecular materials including gels, and nanoparticles. The NPHM-based supramolecular bioactive materials are produced from renewable resources, are simple to prepare, and have demonstrated multi-functionality including slow-release, smart-responsive release, and especially possess powerful biological effects to treat various diseases. In this review, NPHM-based supramolecular bioactive materials have been revealed as an emerging, revolutionary, and promising strategy. The development, advantages, and limitations of NPHM, as well as the advantageous position of NPHM-based materials, are first reviewed. Subsequently, a systematic and comprehensive analysis of the self-assembly strategies specific to seven major classes of NPHM is highlighted. Insights into the influence of NPHM structural features on the formation of supramolecular materials are also provided. Finally, the drivers and preparations are summarized, emphasizing the biomedical applications, future scientific challenges, and opportunities, with the hope of igniting inspiration for future research and applications.

Indexed as

Biocompatible MaterialsBiological ProductsHerbal MedicineHumansNanoparticlesPlants, MedicinalBiocompatible MaterialsBiological Productsbioactive materialsnatural productsself‐assemblystrategy

Identifiers

PMID39033533
PMCPMC11425287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.