Evidence map›Paper›PMID 39033272›Full record

ArticleBMC pediatrics2024

The odds of having obesity in Egyptian children with autism spectrum disorders is higher than stunting compared to healthy developing peers: a national survey.

Ammal M Metwally, Mona A Helmy, Ahmed Aboulghate, Naglaa Abu-Mandil Hassan, Walaa S Mahmoud, Ahmed S Ismail, Salwa M El Shebini, Nihad H Ahmed, Hoda B Mabrok, Maha H Mahmoud and 13 more

Abstract readComparative Study
In one paragraph

Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Ammal M MetwallyCommunity Medicine Research Department/Medical Research and Clinical Studies Institute, National Research Centre, P.O. 12622, Dokki, Cairo, Egypt. ammal_mok@yahoo.com.ORCID http://orcid.org/0000-0003-0575-5202
Mona A HelmyEnvironmental and Occupational Medicine Department, Environmental and climate change Research Institute, National Research Centre, Dokki, Cairo, Egypt.
Ahmed AboulghateCommunity Medicine Research Department/Medical Research and Clinical Studies Institute, National Research Centre, P.O. 12622, Dokki, Cairo, Egypt.
Naglaa Abu-Mandil HassanBiological Anthropology Department/Medical Research and Clinical Studies Institute/National Research Centre, Dokki, Cairo, Egypt.
Walaa S MahmoudBiological Anthropology Department/Medical Research and Clinical Studies Institute/National Research Centre, Dokki, Cairo, Egypt.
Ahmed S IsmailBiological Anthropology Department/Medical Research and Clinical Studies Institute/National Research Centre, Dokki, Cairo, Egypt.
Salwa M El ShebiniNutrition and Food Science Department/Food Technology and Nutrition Division, National Research Centre, P.O: 12622, Dokki, Cairo, Egypt.
Nihad H AhmedNutrition and Food Science Department/Food Technology and Nutrition Division, National Research Centre, P.O: 12622, Dokki, Cairo, Egypt.
Hoda B MabrokNutrition and Food Science Department/Food Technology and Nutrition Division, National Research Centre, P.O: 12622, Dokki, Cairo, Egypt.
Maha H MahmoudNutrition and Food Science Department/Food Technology and Nutrition Division, National Research Centre, P.O: 12622, Dokki, Cairo, Egypt.
Ghada A ElshaarawyCommunity Medicine Research Department/Medical Research and Clinical Studies Institute, National Research Centre, P.O. 12622, Dokki, Cairo, Egypt.
Amal ElsaiedChild with Special Needs Dept./ Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Cairo, Egypt.
Engy A AshaatClinical Genetics Department, Human Genetics and Genome Research Institute, National Research Centre, Dokki, Cairo, Egypt.
Amira S ElRifayChild Health Department, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Cairo, Egypt.
Safaa AbdelhadyDepartment of Psychiatry, Mansoura General Hospital, Ministry of Health and Population, El Dakahlyia, Egypt.
Sherif E EldeebCommunity Medicine Research Department/Medical Research and Clinical Studies Institute, National Research Centre, P.O. 12622, Dokki, Cairo, Egypt.
Mostafa M El-SaiedChild with Special Needs Dept./ Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Cairo, Egypt.
Sahar A El-MasryBiological Anthropology Department/Medical Research and Clinical Studies Institute/National Research Centre, Dokki, Cairo, Egypt.
Nayera E HassanBiological Anthropology Department/Medical Research and Clinical Studies Institute/National Research Centre, Dokki, Cairo, Egypt.
Hala Y BadawyPrevention of disability general directorate, Ministry of Health and Population, Cairo, Egypt.
Nahed A ElghareebPrevention of disability general directorate, Ministry of Health and Population, Cairo, Egypt.
Mohamed AbdelrahmanCommunity Medicine Research Department/Medical Research and Clinical Studies Institute, National Research Centre, P.O. 12622, Dokki, Cairo, Egypt.
Khadija M AlianBiological Anthropology Department/Medical Research and Clinical Studies Institute/National Research Centre, Dokki, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe nutritional status and growth of children with Autism spectrum disorders (ASD) is influenced significantly by two factors; food selectivity behaviors due to their consumption of a limited variety of food and the high incidence of gastrointestinal (GIT) disorders.

aimThis study aimed to assess the nutritional adequacy and growth pattern of ASD children aged three to twelve years compared to their healthy developing peers.

methodsA national comparative, facility-based cross-sectional study was conducted in eight Egyptian governorates on 285 Egyptian children diagnosed with ASD and 224 children who are their relatives as healthy developing peers. Anthropometric measurements were obtained, including weight, height, head circumference, and mid-upper arm circumference. Body Mass Index (BMI) was calculated and all numbers were plotted on WHO growth charts. Assessment of food preferences, and nutrient intake adequacy of children was done using the Food preference questionnaire, and the Dietary Reference Intakes (DRIs) of Egyptian children.

resultsCalorie-dense food and sugar intake were higher among ASD children than their healthy developing peers. ASD children omit some important protein sources such as dairy (COR = 5.2, 95% CI:2.7-9.9), meat, and poultry (COR = 2.7, 95% CI: 1.6-4.7), and a lower intake of fruits and vegetables than their healthy developing peers. For children with ASD in all age groups, a deficiency in the range of 50-60% was detected for vitamins (C, D, B6, thiamine, riboflavin, niacin) and minerals (iron). A deficiency in the range of 60-70% was detected for folate and calcium. A deficiency of vitamin C calcium and iron was also detected for both children with ASD and their healthy developing relatives aged 6 to 12 years. GIT disorders were common among ASD children compared to healthy developing peers (COR = 2.8 to 10.3). Children with ASD had four-fold higher odds of stunting (COR = 4.1, CI: 1.7-10.1), threefold higher odds of being overweight (COR = 3.3, CI: 1.48-7.32), and nearly eleven-fold higher odds of obesity (COR = 11.4, CI: 4.05-32.17) compared to their healthy developing peers.

conclusionASD children are prone to overweight and protein malnutrition. Their intake of fruits and vegetables is inadequate and hence their intake of vitamins and minerals is insufficient, contributing to stunting.

Indexed as

Autism Spectrum DisorderGrowth DisordersPediatric ObesityBody Mass IndexCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesDietEgyptFemaleFood PreferencesHumansMaleNutritional StatusASDAutismEatingGIT disordersGrowth statusNutrition

Identifiers

PMID39033272
PMCPMC11264811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.