Evidence map›Paper›PMID 39033264›Full record

ReviewCNS drugs2024

Current Perspectives on the Clinical Research and Medicalization of Psychedelic Drugs for Addiction Treatments: Safety, Efficacy, Limitations and Challenges.

Anton Gomez-Escolar, Daniel Folch-Sanchez, Joanna Stefaniuk, Zoe Swithenbank, Andreia Nisa, Fleur Braddick, Nazish Idrees Chaudhary, Pim B van der Meer, Albert Batalla

Abstract readReview
PubMed Publisher
In one paragraph

Review in CNS drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anton Gomez-EscolarINAWE Institute, Calle Ciudad Real 28, 28223, Madrid, Spain. antongomezes@gmail.com.ORCID 0000-0001-6957-6196
Daniel Folch-SanchezAddictions Research Group (GRAC), Clínic Foundation for Biomedical Research - Institut d'Investigacions Biomèdiques August Pi Sunyer (FRCB-IDIBAPS), Barcelona, Spain.ORCID 0000-0002-2664-2955
Joanna StefaniukPolish Drug Policy Network, Warsaw, Poland.
Zoe SwithenbankPublic Health Institute, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0003-3915-1618
Andreia NisaAssociação Existências, RECI, Viseu, Portugal.ORCID 0000-0002-1404-5942
Fleur BraddickAddictions Research Group (GRAC), Clínic Foundation for Biomedical Research - Institut d'Investigacions Biomèdiques August Pi Sunyer (FRCB-IDIBAPS), Barcelona, Spain.ORCID 0000-0001-6755-4567
Nazish Idrees ChaudharyLahore School of Behavioural Sciences (LSBS), The University of Lahore, Lahore, Pakistan.ORCID 0000-0002-3404-1252
Pim B van der MeerDepartment of Neurology, University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-3700-8906
Albert BatallaDepartment of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-5010-5121

Funding

Directorate-General for Justice and Consumers Grant No. 957776
6 · The paper itself

Abstract

Mental health disorders and substance use disorders (SUDs) in particular, contribute greatly to the global burden of disease. Psychedelics, including entactogens and dissociative substances, are currently being explored for the treatment of SUDs, yet with less empirical clinical evidence than for other mental health disorders, such as depression or post-traumatic stress disorder (PTSD). In this narrative review, we discuss the current clinical research evidence, therapeutic potential and safety of psilocybin, lysergic acid diethylamide (LSD), ketamine, 3,4-methylenedioxymethamphetamine (MDMA) and ibogaine, particularly in the context of the SUD treatment. Our aim was to provide a balanced overview of the current research and findings on potential benefits and harms of psychedelics in clinical settings for SUD treatment. We highlight the need for more clinical research in this particular treatment area and point out some limitations and challenges to be addressed in future research.

Indexed as

HallucinogensSubstance-Related DisordersBiomedical ResearchHumansHallucinogens

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.