Evidence map›Paper›PMID 39033225›Full record

SynthesisPediatric surgery international2024

Systematic review of the mechanism and assessment of liver fibrosis in biliary atresia.

Jianghua Zhan, Shaowen Liu, Yu Meng, Qianhui Yang, Zhiru Wang, Shujian Zhang, Liang Ge, Li Zhao, Xiaodan Xu, Yilin Zhao and 2 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biliary atresia-related liver fibrosis.Frontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jianghua ZhanTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China. zhanjianghuatj@163.com.
Shaowen LiuTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Yu MengTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Qianhui YangTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Zhiru WangTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Shujian ZhangTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Liang GeTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Li ZhaoTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Xiaodan XuTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Yilin ZhaoTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Xin LiTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.
Xueting WangTianjin Children's Hospital ("Children's Hospital, Tianjin University"), Tianjin, China.

Funding

Tianjin Applied Basic Research Project No.22JCZDJC00290Tianjin Science and Technology Program No.21ZXGWSY00070
6 · The paper itself

Abstract

purposeThis study systematically reviewed our team's research on the mechanism and assessment of liver fibrosis in BA, summarized our experience, and discussed the future development direction.

methodsIn this study, Pubmed and Wanfang databases were searched to collect the literature published by our team on the mechanisms of liver fibrosis in BA and the assessment of liver fibrosis in BA, and the above research results were systematically reviewed.

resultsA total of 58 articles were retrieved. Among the included articles, 25 articles related to the mechanism of liver fibrosis in BA, and five articles evaluated liver fibrosis in BA. This article introduces the key pathways and molecules of liver fibrosis in BA and proposes a new grading system for liver fibrosis in BA.

conclusionsThe new BA liver fibrosis grading method is expected to assess children's conditions, guide treatment, and improve prognosis more accurately. In addition, we believe that the TGF-β1 signaling pathway is the most important in the study of liver fibrosis in BA, and at the same time, the study of EMT occurrence in BA should also be deepened to resolve the controversy on this issue.

Indexed as

Biliary AtresiaLiver CirrhosisHumansPrognosisTransforming Growth Factor beta1Transforming Growth Factor beta1Biliary atresia (BA)GradingLiver fibrosisSystematic review

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.