Evidence map›Paper›PMID 39033194›Full record

ArticleNPJ vaccines2024

A scoping review of global COVID-19 vaccine hesitancy among pregnant persons.

Imaima Casubhoy, Alyssa Kretz, Heang-Lee Tan, Laura A St Clair, Maclaine Parish, Hana Golding, Susan J Bersoff-Matcha, Catherine Pilgrim-Grayson, Leah Berhane, Andrew Pekosz and 5 more

Abstract readScoping Review
In one paragraph

Article in NPJ vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Perceived barriers to accessing vaccination plans in pregnant women in Chile: a qualitative analysis.Archives of public health = Archives belges de sante publique · 2026
    Article
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  11. Trophoblast ferroptosis restricts SARS-CoV-2 spread in the placenta.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Imaima CasubhoyDepartment of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Alyssa KretzDepartment of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-9300-186X
Heang-Lee TanDepartment of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Laura A St ClairW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Maclaine ParishW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Hana GoldingDivision of Viral Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Susan J Bersoff-MatchaOffice of Women's Health, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Catherine Pilgrim-GraysonOffice of Rare Diseases, Pediatrics, Urologic and Reproductive Medicine-Division of Urology, Obstetrics, and Gynecology, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Leah BerhaneOffice of Rare Diseases, Pediatrics, Urologic and Reproductive Medicine-Division of Urology, Obstetrics, and Gynecology, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Andrew PekoszW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-3248-1761
Heba H MostafaDepartment of Pathology, Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Andrea L CoxW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-9331-2462
Irina BurdDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Sabra L KleinDepartment of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-0730-5224
Rosemary MorganDepartment of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA. rosemary.morgan@jhu.edu.

Funding

Johns Hopkins Center of Excellence in Regulatory Science and Innovation (JH-CERSI)U01FD005942 · FDA · JOHNS HOPKINS UNIVERSITY · PI ALEXANDER, G. CALEB · 2016 to 2025
$15.5M
Sex differences in the impact of frailty on vaccine-induced immune responses in community-dwelling older adultsU54AG062333 · NIA · JOHNS HOPKINS UNIVERSITY · PI KLEIN, SABRA L. · 2018 to 2022
$8.9M
FDA HHS U01 FD005942NIA NIH HHS U54 AG062333U.S. Department of Health & Human Services | NIH | Office of Research on Women's Health (NIH Office of Research on Women's Health) U54AG062333U.S. Department of Health & Human Services | U.S. Food and Drug Administration (U.S. Food & Drug Administration) U01FD005942
6 · The paper itself

Abstract

Uptake of the COVID-19 vaccine among pregnant persons is lower than the general population. This scoping review explored pregnant people's attitudes towards the COVID-19 vaccine, reasons for vaccine hesitancy, and whether attitudes about COVID-19 vaccines differ by country of origin. A scoping review was conducted across PubMed, Embase, CINHAL, and Scopus. Inclusion criteria were articles published in English from 2019-2022 focused on attitudes towards COVID-19 vaccination among pregnant persons. Data analysis was done via the 5Cs framework for vaccine hesitancy: Constraints, Complacency, Calculation, Confidence, and Collective Responsibility. 44 articles were extracted. A lack of confidence in vaccine safety was the most prevalent theme of hesitancy among pregnant persons. This was largely driven by a lack of access to information about the vaccine as well as mistrust of the vaccine and medical professionals. Meanwhile, vaccine acceptance was mostly driven by a desire to protect themselves and their loved ones. Overall, COVID-19 vaccine hesitancy among pregnant persons continues to be high. Vaccine hesitancy is primarily driven by fear of the unknown side effects of the vaccine on pregnant persons and their fetuses along with a lack of information and medical mistrust. Some differences can be seen between high income and low- and middle-income countries regarding vaccine hesitancy, showing that a single solution cannot be applied to all who are vaccine hesitant. General strategies, however, can be utilized to reduce vaccine hesitancy, including advocating for inclusion of pregnant persons in clinical trials and incorporating consistent COVID-19 vaccine counseling during prenatal appointments.

Identifiers

PMID39033194
PMCPMC11271279

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.