Evidence map›Paper›PMID 39033144›Full record

ArticleBMC palliative care2024

A nationwide neurosurgical inter-disciplinary service for cancer-related refractory pain.

Morsi Khashan, Ido Strauss, Yehonathan Hochberg, Silviu Brill, Rotem Tellem, Haggai Sharon, Uri Hochberg

Abstract read
In one paragraph

Article in BMC palliative care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Morsi KhashanSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ido StraussSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Yehonathan HochbergSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Silviu BrillSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Rotem TellemSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Haggai SharonSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Uri HochbergSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. urihochberg@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNeurosurgical ablative procedures, such as cordotomy and cingulotomy, are often considered irreversible and destructive but can provide an effective and individualized solution for cancer-related refractory pain, when all other approaches have been unsuccessful. This paper provides an in-depth exploration of a novel approach to managing refractory cancer pain. It involves an interdisciplinary team led by a neurosurgeon at a renowned national referral center.

methodsa retrospective analysis of the medical records of all sequential patients who underwent their initial evaluation at our interdisciplinary refractory cancer pain clinic from February 2017 to January 2023.

resultsA total of 207 patients were examined in the clinic for a first visit during the study period. All patients were referred to the clinic due to severe pain that was deemed refractory by the referring physician. The mean age was 61 ± 12.3 years, with no significant sex difference (P = 0.58). The mean ECOG Performance Status score was 2.35. Conservative measures had not yet been exhausted in 28 patients (14%) and 9 patients were well controlled (4%). Neurosurgical ablative procedures were recommended for 151 (73%) of the patients. Sixty-six patients (32%) eventually underwent the procedure. 91 patients (44%) received a negative recommendation for surgery. Thirty-five patients (17%) were referred for further invasive procedures at the pain clinic.

conclusionAn Interdisciplinary cooperation between palliative care specialists, pain specialists, and neurosurgeons ensures optimal patient selection and provides safe and effective neurosurgery for the treatment of refractory cancer-related pain.

Indexed as

Intractable PainAdultAgedCancer PainFemaleHumansMaleMiddle AgedNeurosurgical ProceduresPain ManagementPatient Care TeamRetrospective StudiesAblative proceduresCancer painInterdisciplinaryPalliative careRefractory pain

Identifiers

PMID39033144
PMCPMC11264704

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.