Evidence map›Paper›PMID 39032005›Full record

ArticleClinical and translational medicine2024

Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma.

Natália Pinto de Almeida, Ágnes Judit Jánosi, Runyu Hong, Ahmad Rajeh, Fábio Nogueira, Leticia Szadai, Beata Szeitz, Indira Pla Parada, Viktória Doma, Nicole Woldmar and 28 more

Abstract readLetterCase Reports
In one paragraph

Article in Clinical and translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Natália Pinto de AlmeidaLaboratory of Proteomics/LADETEC, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.
Ágnes Judit JánosiDepartment of Dermatology and Allergology, University of Szeged, Szeged, Hungary.
Runyu HongInstitute for Systems Genetics, NYU Grossman School of Medicine, New York City, New York, USA.ORCID 0000-0002-0941-351X
Ahmad RajehDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Fábio NogueiraLaboratory of Proteomics/LADETEC, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.
Leticia SzadaiDepartment of Dermatology and Allergology, University of Szeged, Szeged, Hungary.
Beata SzeitzDepartment of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary.ORCID 0000-0001-6414-0537
Indira Pla ParadaSection for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.ORCID 0000-0002-0839-7829
Viktória Doma2nd Department of Pathology, Semmelweis University, Budapest, Hungary.
Nicole WoldmarClinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.
Jéssica GuedesLaboratory of Proteomics/LADETEC, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.
Zsuzsanna ÚjfaludiDepartment of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Aron BarthaDepartment of Bioinformatics, Semmelweis University, Budapest, Hungary.
Yonghyo KimData Convergence Drug Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, South Korea.
Charlotte WelinderDivision of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Bo BaldetorpDivision of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Lajos Vince KeményDepartment of Dermatology, Venerology and Dermatooncology, Semmelweis University, Budapest, Hungary.
Zoltan PahiDepartment of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Guihong WanDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Nga NguyenDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Tibor PankotaiDepartment of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Balázs GyőrffyDepartment of Bioinformatics, Semmelweis University, Budapest, Hungary.
Krzysztof PawłowskiSection for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.
Peter HorvatovichClinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.
Attila Marcell SzaszDepartment of Bioinformatics, Semmelweis University, Budapest, Hungary.
Aniel SanchezSection for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.
Magdalena KurasClinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.ORCID 0000-0002-9479-423X
Jimmy Rodriguez MurilloClinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.
Lazaro BetancourtSection for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.ORCID 0000-0001-8207-7041
Gilberto B DomontProteomics Unit, Institute of Chemistry, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.
Yevgeniy R SemenovDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Kun-Hsing YuDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA.
Ho Jeong KwonChemical Genomics Global Research Lab, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.ORCID 0000-0002-6919-833X
István Balázs NémethDepartment of Dermatology and Allergology, University of Szeged, Szeged, Hungary.
David FenyőInstitute for Systems Genetics, NYU Grossman School of Medicine, New York City, New York, USA.
Elisabet WieslanderSection for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.
György Marko-VargaClinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.
Jeovanis GilSection for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.ORCID 0000-0003-3601-3893

Funding

Robust, Generalizable, and Fair Machine Learning Models for BiomedicineR35GM142879 · NIGMS · HARVARD MEDICAL SCHOOL · PI YU, KUN-HSING · 2021 to 2025
$2.4M
Mitigating Hematologic Adverse Events in Patients with Myeloid Malignancies: A Novel Causal Artificial Intelligence ApproachR01HL174679 · NHLBI · HARVARD MEDICAL SCHOOL · PI Kun-Hsing Yu · 2024 to 2026
$2.3M
Explainable Artificial Intelligence for Melanoma Recurrence Prediction via Integrative Modeling of Multiplexed Imaging with Transcriptomics and HistopathologyK99CA286966 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WAN, GUIHONG · 2024 to 2025
$352k
Apotekarsocieteten 2023-0324-HT-PDCAPES 88887.130697CNPq 308341-2019-8CNPq 440613/2016-7DOD Peer Reviewed Cancer Research Program HT9425-23-1-0523FAPERJ E-26/210.173/2018Fru Berta Kamprads StiftelseIngaBritt och Arne Lundbergs ForskningsstiftelseNCI NIH HHS K99 CA286966NCI NIH HHS L30 CA264747NHLBI NIH HHS R01 HL174679NIGMS NIH HHS R35 GM142879NIGMS NIH HHS R35GM142879
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MelanomaProto-Oncogene Proteins B-rafFemaleHumansMaleMiddle AgedMitochondriaMutationNeoplasm MetastasisBRAF protein, humanProto-Oncogene Proteins B-raf

Identifiers

PMID39032005
PMCPMC11259597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.