ArticleEuropean journal of neurology2024
Ambient air pollution, covert cerebrovascular disease and cognition: results from the ISSYS study.
Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ambient air pollution and childhood obesity from infancy to late childhood: An individual participant data meta-analysis of 10 European birth cohorts.Environment international · 2025Pooled it
- Regional Disparities in Stroke Hospitalization and Mortality Associated with Long-Term Fine Particulate Matter Exposure: A Nationwide Ecological Study in Spain.Medical sciences (Basel, Switzerland) · 2026Article
- Occupational dust exposure and cerebral small vessel disease: a public health perspective on prevention and early detection.Frontiers in medicine · 2026Review
- Fine particulate matter exposure and risk of scooter collisions among older adults.Injury epidemiology · 2025Article
- A population-based study on meteorological conditions in association with motor vehicle collisions among people with type 2 diabetes.Environmental health and preventive medicine · 2025Article
- Ambient air pollution, covert cerebrovascular disease and cognition: results from the ISSYS study.European journal of neurology · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
background and purposeAlthough air pollution (AP) has been associated with stroke and dementia, data regarding its relationship with covert cerebrovascular disease (cCVD) and cognition over time are sparse. The aim of this study was to explore these relationships.
methodsA prospective population-based study of 976 stroke-free and non-demented individuals living in Barcelona, Spain, was conducted during 2010-2016. A land use regression model was used to estimate the exposure of each participant to AP: NO
resultsAt baseline, 99 participants (10.1%) had covert brain infarcts and 91 (9.3%) had extensive periventricular white matter hyperintensities (WMHs). Marked subcortical WMH progression was seen in 19.7%; the incidence of other covert cerebrovascular lessons ranged between 5% and 6% each. PM
conclusionsAir pollutant predicts the presence and accumulation of cCVD. Its impact on cognitive impairment remains to be determined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.