Evidence map›Paper›PMID 39031220›Full record

ArticleLasers in medical science2024

A mechanistic study on the toluidine blue/ photodynamic therapy inhibition of lipopolysaccharide-induced inflammatory response in rat gingival fibroblasts.

Shuang Zhao, Yao Fu, Yang Li, Jianan Lin, Xin Su

Abstract read
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In one paragraph

Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuang ZhaoDepartment of Stomatology, The Sixth Affiliated Hospital of Harbin Medical University, No. 998 Aiying Street, Songbei District, Harbin, Heilongjiang, 150023, China.
Yao FuNational Institutes for Food and Drug Control, No. 31, Huatuo Road, Daxing District, Beijing, 102629, China.
Yang LiDepartment of Stomatology, The Sixth Affiliated Hospital of Harbin Medical University, No. 998 Aiying Street, Songbei District, Harbin, Heilongjiang, 150023, China.
Jianan LinDepartment of Stomatology, The Sixth Affiliated Hospital of Harbin Medical University, No. 998 Aiying Street, Songbei District, Harbin, Heilongjiang, 150023, China.
Xin SuDepartment of Stomatology, The Sixth Affiliated Hospital of Harbin Medical University, No. 998 Aiying Street, Songbei District, Harbin, Heilongjiang, 150023, China. HYD20010901@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this research was to investigate the effect of toluidine blue (TB) mediated photodynamic therapy (PDT) on the inhibition of lipopolysaccharide (LPS)-induced inflammation in rat gingival fibroblasts through in vitro experiments. Rat gingival fibroblasts were divided into five groups: (1) control, (2) LPS treatment, (3) laser treatment, (4) TB treatment (1.0 µg/mL), and (5) PDT treatment (TB plus laser irradiation at 320 mW/cm

Indexed as

FibroblastsGingivaLipopolysaccharidesOsteoprotegerinPhotochemotherapyRANK LigandTolonium ChlorideAnimalsCells, CulturedCell SurvivalInflammationNF-kappa BPhosphorylationPhotosensitizing AgentsRatsLipopolysaccharidesNF-kappa BOsteoprotegerinPhotosensitizing AgentsRANK LigandTolonium ChlorideDiode laserFibroblastsPeriodontitisPhotodynamic therapyToluidine blue

Identifiers

PMID39031220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.