Evidence map›Paper›PMID 39030968›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2024

Persistently elevated joint contact stress after periacetabular osteotomy is associated with joint failure at minimum 10-year follow-up.

Holly D Aitken, Jessica E Goetz, Natalie A Glass, Aspen Miller, Dominic J L Rivas, Robert W Westermann, Todd O McKinley, Michael C Willey

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Holly D AitkenDepartment of Orthopedics & Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID 0000-0001-5419-5489
Jessica E GoetzDepartment of Orthopedics & Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID 0000-0002-7197-5978
Natalie A GlassDepartment of Orthopedics & Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Aspen MillerDepartment of Orthopedics & Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Dominic J L RivasDepartment of Orthopedics & Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID 0000-0003-0822-3738
Robert W WestermannDepartment of Orthopedics & Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Todd O McKinleyMethodist Hospital, Indiana University Health, Indianapolis, Indiana, USA.ORCID 0000-0001-6354-7685
Michael C WilleyDepartment of Orthopedics & Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID 0000-0002-6922-8471

Funding

UI INITIATIVE FOR MINORITY STUDENT DEVELOPMENT PROGRAMR25GM058939 · NIGMS · UNIVERSITY OF IOWA · PI ADAMS-PHILLIPS, LORI C, FORBES, TORI · 1999 to 2021
$6.9M
NIGMS NIH HHS R25 GM058939NIGMS NIH HHS R25GM058939Orthopaedic Research and Education Foundation Career Development Grant 17-001
6 · The paper itself

Abstract

Periacetabular osteotomy (PAO) is a common treatment for prearthritic hip dysplasia. The goal of this investigation was to determine if computationally assessed hip contact mechanics are associated with joint failure at minimum 10-year follow-up. One hundred patients with hip dysplasia (125 hips) completed patient-reported outcomes an average of 13.8 years (range 10.0-18.0 years) after PAO. 63/125 hips were classified as having failed: 26 converted to total hip arthroplasty (THA) and 37 with significant disability indicated by modified Harris Hip Score (mHHS) ≤ 70. Differences in discrete element analysis-computed contact mechanics were compared between (1) preserved and failed hips, (2) preserved hips and hips that failed by THA, and (3) preserved hips and hips that failed by mHHS ≤ 70. Failed hips had significantly higher preoperative contact stress and exposure metrics (p < 0.001-0.009) than preserved hips. Failed hips also had significantly higher postoperative peak contact stress (p = 0.018), higher mean contact stress (p < 0.001), and smaller contact area (p = 0.044). When assessed based on type of failure, hips that failed by THA had significantly higher postoperative contact stress and exposure metrics than preserved hips (p < 0.001-0.020). In hips that failed by mHHS ≤ 70, mean postoperative contact stress exposure was significantly higher compared to preserved hips (p = 0.043). Despite improved radiographic measures of dysplasia after PAO, pathologic joint contact mechanics can persist and predict treatment failure at minimum 10 years after surgery. Operative and nonoperative techniques specifically intended to reduce harmful contact mechanics in dysplastic hips may have the potential to further improve clinical outcomes after PAO.

Indexed as

OsteotomyAcetabulumAdolescentAdultArthroplasty, Replacement, HipFemaleFollow-Up StudiesHip DislocationHip JointHumansMaleMiddle AgedStress, MechanicalYoung Adultcontact stressdiscrete element analysiship dysplasiaosteoarthritisperiacetabular osteotomy

Identifiers

PMID39030968
PMCPMC11654831

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.