ArticleJournal of periodontal research2025
Performance of three artificial intelligence (AI)-based large language models in standardized testing; implications for AI-assisted dental education.
Article in Journal of periodontal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Accuracy of Large Language Models in Answering Dental Examination Questions: A Systematic Review and Meta-Analysis.International dental journal · 2026Pooled it
- Can Large Language Models Serve as Reliable Tools for Information in Dentistry? A Systematic Review.International dental journal · 2025Pooled it
- Accuracy of Large Language Models When Answering Clinical Research Questions: Systematic Review and Network Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Effect of artificial intelligence-assisted personalized feedback on radiographic diagnostic performance of dental students: a controlled study.BMC medical education · 2025Trial
- Misaligned by design: evaluating and deploying generative AI for the real-world conditions of primary care: a Nordic and European perspective.Scandinavian journal of primary health care · 2026Article
- Large Language Models and Retrieval-Augmented Platforms for the Diagnosis and Management of Periodontal Diseases: A Blinded Expert-Rated Comparative Study of 11 Systems.Journal of clinical periodontology · 2026Article
- Evaluating Guideline Adherence in Gemini-Powered Dental Trauma Workflows: Standalone Gemini Chat vs. Document-Grounded NotebookLM.Dental traumatology : official publication of International Association for Dental Traumatology · 2026Article
- Emerging, personalized, and minimally invasive technologies for periodontal and peri-implant soft and hard tissue regenerative therapy.Journal of periodontology · 2026Review
- Artificial intelligence performance in the emergency medicine subspecialty examination conducted in Türkiye.Medicine · 2026Article
- Evaluating Dental Students' Perspectives on Artificial Intelligence (AI)-Driven Large Language Models in Education in Saudi Arabia.European journal of dental education : official journal of the Association for Dental Education in Europe · 2026Article
- Accuracy and Temporal Consistency of ChatGPT and Gemini in Responding to Textbook and Patient-Oriented Dental Bleaching Questions: A Multi-Session Comparative Study.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Article
- A comparative evaluation of large language models in diagnosis and treatment planning in restorative dentistry.BMC oral health · 2026Article
- Multidimensional evaluation of large language models on the AAP in-service examination: Assessing accuracy, calibration, and citation reliability.PLOS digital health · 2026Article
- Evaluating large language model`s performance in answering principles of health course questions.Scientific reports · 2026Article
- Comparative analysis of large language models as decision support tools in oral pathology.Scientific reports · 2026Article
- Comparing ChatGPT and Dental Students' Performance in an Introduction to Dental Anatomy Examination: A Cross-Sectional Study.European journal of dentistry · 2026Article
- Artificial intelligence and immersive digital technologies in periodontal education: a systematic review.Frontiers in oral health · 2026Review
- Applications and potential of ChatGPT in dentistry: Scoping review of research perspectives.Journal of dental sciences · 2026Review
- Artificial intelligence in periodontics and peri-implant medicine: from diagnosis to precision care.Frontiers in dental medicine · 2026Review
- Large language models as data-driven engines for benchmarking preventive and clinical knowledge in Chinese dental examinations.Frontiers in oral health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe emerging rise in novel computer technologies and automated data analytics has the potential to change the course of dental education. In line with our long-term goal of harnessing the power of AI to augment didactic teaching, the objective of this study was to quantify and compare the accuracy of responses provided by ChatGPT (GPT-4 and GPT-3.5) and Google Gemini, the three primary large language models (LLMs), to human graduate students (control group) to the annual in-service examination questions posed by the American Academy of Periodontology (AAP).
methodsUnder a comparative cross-sectional study design, a corpus of 1312 questions from the annual in-service examination of AAP administered between 2020 and 2023 were presented to the LLMs. Their responses were analyzed using chi-square tests, and the performance was juxtaposed to the scores of periodontal residents from corresponding years, as the human control group. Additionally, two sub-analyses were performed: one on the performance of the LLMs on each section of the exam; and in answering the most difficult questions.
resultsChatGPT-4 (total average: 79.57%) outperformed all human control groups as well as GPT-3.5 and Google Gemini in all exam years (p < .001). This chatbot showed an accuracy range between 78.80% and 80.98% across the various exam years. Gemini consistently recorded superior performance with scores of 70.65% (p = .01), 73.29% (p = .02), 75.73% (p < .01), and 72.18% (p = .0008) for the exams from 2020 to 2023 compared to ChatGPT-3.5, which achieved 62.5%, 68.24%, 69.83%, and 59.27% respectively. Google Gemini (72.86%) surpassed the average scores achieved by first- (63.48% ± 31.67) and second-year residents (66.25% ± 31.61) when all exam years combined. However, it could not surpass that of third-year residents (69.06% ± 30.45).
conclusionsWithin the confines of this analysis, ChatGPT-4 exhibited a robust capability in answering AAP in-service exam questions in terms of accuracy and reliability while Gemini and ChatGPT-3.5 showed a weaker performance. These findings underscore the potential of deploying LLMs as an educational tool in periodontics and oral implantology domains. However, the current limitations of these models such as inability to effectively process image-based inquiries, the propensity for generating inconsistent responses to the same prompts, and achieving high (80% by GPT-4) but not absolute accuracy rates should be considered. An objective comparison of their capability versus their capacity is required to further develop this field of study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.