Evidence map›Paper›PMID 39030703›Full record

SynthesisPathogens and global health2024

Global and regional mortality statistics of nipah virus from 1994 to 2023: a comprehensive systematic review and meta-analysis.

Srivatsa Surya Vasudevan, Arun Subash, Fena Mehta, Tiba Yamin Kandrikar, Rupak Desai, Kaif Khan, Sneha Khanduja, Aakanksha Pitliya, Lekhya Raavi, Sai Gautham Kanagala and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pathogens and global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Nipah virus molecular detection from whole blood and respiratory swabs in a rapid field-ready protocol.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Srivatsa Surya VasudevanDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Jacksonville, FL, USA.
Arun SubashDepartment of Academics, Dow University of Health Sciences, Karachi, Pakistan.
Fena MehtaDepartment of Academics, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India.
Tiba Yamin KandrikarDepartment of Dermatology and Venerology, Yerevan State Medical University, Yerevan, Armenia.
Rupak DesaiIndependent Researcher, Atlanta, GA, USA.
Kaif KhanDepartment of Biosciences, Jamia Millia Islamia, Delhi, India.
Sneha KhandujaDepartment of Academics, Dr. Baba Saheb Ambedkar Medical College and Hospital, New Delhi, India.
Aakanksha PitliyaDepartment of Medicine, Pamnani Hospital and Research Center, Mandsaur, MP, India.
Lekhya RaaviDepartment of Critical Care Medicine, Mayo Clinic, Jacksonville, FL, USA.
Sai Gautham KanagalaDepartment of Internal Medicine, Metropolitan Hospital Center, New York, USA.
Piyush GondaliyaDepartment of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mortality rate of Nipah virus (NiV) can vary in different regions, and its pattern across timelines has yet to be assessed. The primary objective is to perform a comparative analysis of mortality rates across different timelines and countries. Articles reporting NiV mortality from inception to November 2023 were analyzed in PubMed, Ovid Embase, Scopus, and Web of Science databases. A meta-analysis utilizing random-effects models determined the mortality rate secondary to NiV complications. The initial search strategy yielded 1213 records, of which 36 articles met the inclusion criteria, comprising 2736 NiV patients. The Global mortality rate of the Nipah virus in the 2014-2023 decade was 80.1% (CI: 68.7-88.1%), indicating a significant 24% increase compared to the preceding decade (2004-2013) with a mortality rate of 54.1% (CI: 35.5-71.6%). Among the countries analyzed for overall mortality from 1994-2023, India experienced the highest mortality rate at 82.7% (CI: 74.6-88.6%), followed by Bangladesh at 62.1% (CI: 45.6-76.2%), Philippines at 52.9% (CI: 30-74.5%), Malaysia at 28.9% (CI: 21.4-37.9%), and Singapore at 21% (CI: 8-45%). Subgroup analysis revealed that India consistently had the highest mortality rate for the past two decades (91.7% and 89.3%). The primary complication leading to mortality was encephalitis, accounting for 95% of cases. This systematic review and meta-analysis revealed a noteworthy surge in NiV mortality rates, particularly in the current decade (2014-2023). The escalation, with India reporting a concerning level of mortality of 89.3-91.7% in the past decades, signifies a pressing public health challenge.

Indexed as

Global HealthHenipavirus InfectionsNipah VirusHumanscase fatality rateglobal death ratehenipavirusMortality ratenipah virus

Identifiers

PMID39030703
PMCPMC11441053

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.