Evidence map›Paper›PMID 39030696›Full record

ArticleSchizophrenia bulletin2025

Reasons for Discharge in a National Network of Early Psychosis Intervention Programs.

Peter L Phalen, William R Smith, Nev Jones, Samantha J Reznik, C Nathan Marti, John Cosgrove, Molly Lopez, Monica E Calkins, Melanie E Bennett

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peter L PhalenDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-4219-3475
William R SmithDepartment of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-6611-0817
Nev JonesSchool of Social Work, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Samantha J ReznikTexas Institute for Excellence in Mental Health, Steve Hicks School of Social Work, University of Texas at Austin, Austin, Texas, USA.
C Nathan MartiTexas Institute for Excellence in Mental Health, Steve Hicks School of Social Work, University of Texas at Austin, Austin, Texas, USA.
John CosgroveWestat, Rockville, Maryland, USA.
Molly LopezTexas Institute for Excellence in Mental Health, Steve Hicks School of Social Work, University of Texas at Austin, Austin, Texas, USA.
Monica E CalkinsDepartment of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-0546-0263
Melanie E BennettDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Funding

Signature ProjectP50MH127511 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BROWN, GREGORY K · 2021 to 2025
$14.4M
Early Psychosis Intervention Network (EPINET): Data Coordinating CenterU24MH120591 · NIMH · WESTAT, INC. · PI ROSENBLATT, ABRAM · 2019 to 2023
$10.0M
SCHIZOPHRENIA: A NEUROPSYCHIATRIC PERSPECTIVET32MH019112 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E · 1990 to 2024
$6.2M
Improving Engagement in Black Clients Participating in Coordinated Specialty Care: A Mixed Methods Pilot StudyR01MH120550 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI BENNETT, MELANIE E. · 2020 to 2023
$5.9M
Advancing the Early Psychosis Intervention Network in Texas (EPINET-TX)R01MH120599 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI LOPEZ, MOLLY A. · 2020 to 2023
$5.5M
Optimizing Disability Benefit Decisions and Outcomes in First Episode PsychosisR01MH125868 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLDMAN, HOWARD H, JONES, GENEVRA · 2022 to 2024
$1.6M
Targeting Emotion Dysregulation to Reduce Suicide in People with PsychosisK23MH125024 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI PHALEN, PETER LEE · 2022 to 2025
$711k
NIH HHS 1K23MH125024-01A1NIMH NIH HHS K23 MH125024NIMH NIH HHS P50 MH127511NIMH NIH HHS R01 MH120550NIMH NIH HHS R01 MH120599NIMH NIH HHS R01 MH125868NIMH NIH HHS T32 MH019112NIMH NIH HHS U24 MH120591
6 · The paper itself

Abstract

backgroundDischarge from early psychosis intervention is a critical stage of treatment that may occur for a variety of reasons. This study characterizes reasons for discharge among participants in early psychosis intervention programs participating in the Early Psychosis Intervention Network (EPINET) which comprises >100 programs in the United States organized under 8 academic hubs. STUDY

designWe analyzed 1787 discharges, focusing on program completion, unilateral termination by the client/family, and lost contact with the client/family. We performed exploratory analyses of demographic, clinical, and functional predictors of discharge reason. Variables predictive of discharge type were included in multilevel logistic regressions, allowing for the estimation of predictors of discharge reason and variability in rates by program and hub. STUDY

resultsAn estimated 20%-30% of enrolled patients completed the program. Program completion rates were higher among participants who were older on admission, had lower negative symptoms severity, spent more time in education, employment, or training, and who were covered by private insurance (a close proxy for socioeconomic status). Programs were more likely to lose contact with male participants, Black participants, and participants who were never covered by private insurance. After accounting for patient-level factors, there was substantial program-level variation in all 3 discharge outcomes, and hub-level variability in the proportion of participants who completed the program. The impact of race on program completion varied substantially by program.

conclusionsParticipants were discharged from early psychosis intervention services for diverse reasons, some of which were associated with sociocultural factors. Disengagement is a widespread problem affecting all hubs.

Indexed as

Early Medical InterventionPatient DischargePsychotic DisordersSchizophreniaAdolescentAdultFemaleHumansMaleUnited StatesYoung AdultCoordinated Specialty Careearly interventionEPINETschizoaffectiveschizophrenia

Identifiers

PMID39030696
PMCPMC12077663

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.