Evidence map›Paper›PMID 39030671›Full record

ArticleJournal of intellectual disabilities : JOID2026

Constipation prevalence and risk from prescribed medications in people with intellectual disability: Findings from an English mortality programme.

Christina Roberts, Jonathon Ding, Delia Bishara, Sahar Riaz, Rory Sheehan, Adam White, Andre Strydom, Umesh Chauhan

Abstract read
In one paragraph

Article in Journal of intellectual disabilities : JOID, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christina RobertsResearch Facilitation and Delivery Unit, Applied Health Research hub, University of Central Lancashire, UK.ORCID 0000-0001-6226-0519
Jonathon DingInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Delia BisharaInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.ORCID 0000-0001-6226-0519
Sahar RiazRoyal College of Surgeons in Ireland, Ireland.
Rory SheehanInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Adam WhiteInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Andre StrydomInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Umesh ChauhanSchool of Medicine, University of Central Lancashire, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constipation is common in people with intellectual disability, with case reports of associated deaths. Risk factors include lifestyle factors, health conditions, and certain medications. We aimed to explore constipation in a sample of people with intellectual disability who died in 2021. We described prevalence of constipation, causes of death and the risk of secondary constipation from prescribed medications. Medications were scored based on the risk of constipation indicated in the drug profile. Forty-eight percent of the sample had constipation. Half of the sample were prescribed at least two medications that are commonly associated with side effects of constipation. There were high rates of antipsychotic (30%) and laxative (40%) drug prescription. Five people with a history of constipation died of causes of death associated with constipation. Our findings highlight the risk of secondary constipation due to prescribed medication and the seriousness of the condition in people with intellectual disability.

Indexed as

Antipsychotic AgentsConstipationIntellectual DisabilityLaxativesPrescription DrugsAdolescentAdultComorbidityEnglandFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsYoung AdultAntipsychotic AgentsLaxativesPrescription Drugsavoidable mortalityconstipationIntellectual disabilitymedication

Identifiers

PMID39030671
PMCPMC13519064

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.