Evidence map›Paper›PMID 39030641›Full record

ArticleEuropean journal of medical research2024

A novel nanohydroxyapatite/polyamide 66 strut for reducing subsidence after one-level anterior cervical corpectomy and fusion: a finite-element study.

Weiyang Zhong, Ke Tang, Zhengxue Quan

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Article in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Weiyang ZhongDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. 492467112@qq.com.
Ke TangDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhengxue QuanDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Funding

Chongqing Natural Science Foundation Project CSTB2022NSCQ-MSX0070the medical program of Chongqing health and science,technology commission 2021MSXM285
6 · The paper itself

Abstract

backgroundThe aim of this study is to introduce a novel nanohydroxyapatite/polyamide 66(n-HA/PA66)n strut to improve biomechanical performance and reduce subsidence.

methodsOne validated intact and 2 ACCF-simulated C3-C7 cervical spine models were developed (old strut: Group A, new strut: Group B). In the ACCF models, C5 underwent corpectomy and was fixed by an anterior cervical plate. Screw angles were categorized as 1 (0 ) and 2 (45 ) and divided into 4 groups, A1, A2, B1 and B2, for each model. An axial force of 74 N and a moment couple of 1.0 Nm were imposed on the C3 vertebra. The range of motion (ROM) of each segment and the stress distribution on the screw-vertebra interface, strut, and strut-endplate interface were recorded and analysed.

resultsThere was no significant difference in ROM between Group A and Group B during bending, extension and rotation under 74 N axial pressure. The stress concentration on the strut body in Group A was higher than that in Group B. The peak stress values at the screw-vertebral interface in Groups A1 and A2 were higher than those in Groups B1 and B2, except for during extension and lateral bending. Under axial pressure, the peak stress values at the strut body-endplate interface during bending, extension and rotation were lower in the A1 and A2 groups than in the B1 and B2 groups. The Group B model showed much higher graft stress than the Group A model.

conclusionsBased on finite-element analysis, compared with the old strut, the novel strut showed better biomechanical performance at the screw-vertebra interface.

Indexed as

Cervical VertebraeDurapatiteFinite Element AnalysisNylonsSpinal FusionBiomechanical PhenomenaBone ScrewsHumansRange of Motion, ArticularDurapatiteNylonsAnterior cervical corpectomy and fusionFinite-element studyn-HA/PA66 strut

Identifiers

PMID39030641
PMCPMC11264631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.