Evidence map›Paper›PMID 39030417›Full record

ArticlePain and therapy2024

A Retrospective Analysis of Disease Epidemiology, Comorbidity Burden, Treatment Patterns, and Healthcare Resource Utilization of Migraine in the United Arab Emirates.

Alessandro Terruzzi, Abubaker AlMadani, Suhail Al-Rukn, Mohamed Farghaly, Sara A Dallal, Mostafa Zayed, Nora Vainstein, Mohamed Fathy, Anup Uboweja, Ashok Natarajan and 3 more

Abstract read
In one paragraph

Article in Pain and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alessandro TerruzziNeurology Department, Mediclinic City Hospital, Dubai, UAE.
Abubaker AlMadaniDepartment of Neurology, Rashid Hospital, Dubai, UAE.
Suhail Al-RuknDepartment of Neurology, Rashid Hospital, Dubai, UAE.
Mohamed FarghalyHealth Economics and Insurance Policies Department, Dubai Health Authority, Dubai, UAE.
Sara A DallalDubai Health Authority, Dubai, UAE.
Mostafa ZayedHealth Economics and Outcomes Research (HEOR), Pfizer, Dubai, UAE.
Nora VainsteinCardiovascular Scientific Expert Emerging Market, Pfizer, Dubai, UAE.
Mohamed FathyRegional Internal Medicine, Pfizer, Dubai, UAE.
Anup UbowejaValue and Implementation Global Medical and Scientific Affairs, MSD, Mumbai, Maharashtra, India.
Ashok NatarajanConsulting Services, IQVIA, London, UK.
Kumaresan SubramanyamEMEA Consulting Services, IQVIA, Bangalore, India.
Badrinath C RamachandracharReal-World Evidence, IQVIA, Dubai, UAE.
Ali AljabbanPfizer, Dubai Media City, P.O. Box 502749, Dubai, UAE. ali.aljabban@pfizer.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMigraine is a recurrent, disabling neurological disorder with a substantial global disease burden. However, limited real-world data are available on the patient characteristics, treatment patterns, comorbidities, and economic burden of migraine in the United Arab Emirates (UAE). In this study, we evaluated the disease burden, comorbidities, treatment patterns, specialties involved in migraine diagnosis, and healthcare resource utilization (HCRU) and associated costs in patients with migraine in Dubai, UAE.

methodsA retrospective, secondary database cohort study was conducted from 01 January 2014 to 31 March 2022 using the Dubai Real-World Database. Patients aged ≥ 18 years with at least one diagnosis claim for migraine with continuous enrollment during the study period were included. Patients were stratified into treatment sub-cohorts. Outcomes were evaluated in terms of clinical characteristics, comorbidities, specialists visited, treatment patterns, and HCRU.

resultsThe study included 203,222 patients (mean age: 40 years), with male predominance (55.4%). About 13.4% of patients had specific cardiovascular comorbidities. Frequently prescribed drug classes were nonsteroidal anti-inflammatory drugs (84.4%), triptans (29.8%), and beta-blockers (12.8%), while only 1.0% of patients with migraine were prescribed newer medications like calcitonin gene-related peptide antagonists. General medicine was the most frequently visited specialty on the index date (51.5%). The all-cause and migraine-specific median gross costs during the 12-month post-index period were US $1252.6 (2.4-564,740.7) and US $198.1 (0-168,903.3) respectively, with maximum contribution from inpatients. The contribution of migraine-specific median costs to all-cause median costs was highest for the diagnosis-related group (64.9%), followed by consumables (35.2%), medications (32.0%), procedures (24.5%), and services (24.5%).

conclusionMigraine significantly impacts healthcare costs in the UAE. The role of newer therapies in migraine management should be explored to reduce the associated socioeconomic burden and improve patients' quality of life.

Indexed as

Comorbiditye-Claims data studyEpidemiologyHealthcare resource utilizationMigraineTreatment patterns

Identifiers

PMID39030417
PMCPMC11393247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.