Evidence map›Paper›PMID 39030355›Full record

ReviewAdvances in anatomy, embryology, and cell biology2024

How Do Environmental Toxicants Affect Oocyte Maturation Via Oxidative Stress?

Reza Rajabi-Toustani, Qinan Hu, Shuangqi Wang, Huanyu Qiao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in anatomy, embryology, and cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Reza Rajabi-ToustaniDepartment of Comparative Biosciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Qinan Hu *Department of Comparative Biosciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Shuangqi Wang *Department of Comparative Biosciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Huanyu QiaoDepartment of Comparative Biosciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA. hqiao@illinois.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammals, oogenesis initiates before birth and pauses at the dictyate stage of meiotic prophase I until luteinizing hormone (LH) surges to resume meiosis. Oocyte maturation refers to the resumption of meiosis that directs oocytes to advance from prophase I to metaphase II of meiosis. This process is carefully modulated to ensure a normal ovulation and successful fertilization. By generating excessive amounts of oxidative stress, environmental toxicants can disrupt the oocyte maturation. In this review, we categorized these environmental toxicants that induce mitochondrial dysfunction and abnormal spindle formation. Further, we discussed the underlying mechanisms that hinder oocyte maturation, including mitochondrial function, spindle formation, and DNA damage response.

Indexed as

OocytesOogenesisOxidative StressAnimalsDNA DamageEnvironmental PollutantsFemaleHumansMitochondriaEnvironmental PollutantsEnvironmental toxicantsMitochondriaOocyte maturationOxidative stressSignaling pathwaySpindle

Identifiers

PMID39030355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.