Evidence map›Paper›PMID 39029333›Full record

Trial reportBehaviour research and therapy2024

Guided internet-based LGBTQ-affirmative cognitive-behavioral therapy: A randomized controlled trial among sexual minority men in China.

Mengyao Yi, Xianhong Li, Danielle Chiaramonte, Shufang Sun, Si Pan, Zachary Soulliard, Benjamin E Eisenstadt, Brjánn Ljótsson, Ashley Hagaman, John Pachankis

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Behaviour research and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Trial
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  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mengyao YiXiangya School of Nursing, Central South University, Changsha, Hunan Province, China.
Xianhong LiXiangya School of Nursing, Central South University, Changsha, Hunan Province, China. Electronic address: xianhong_li@csu.edu.cn.
Danielle ChiaramonteYale School of Public Health, Yale University, New Haven, CT, USA.
Shufang SunBrown University School of Public Health, Providence, RI, USA.
Si PanThe Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Zachary SoulliardMiami University, Oxford, OH, USA.
Benjamin E EisenstadtYale School of Public Health, Yale University, New Haven, CT, USA.
Brjánn LjótssonKarolinska Institutet, Stockholm, Sweden.
Ashley HagamanYale School of Public Health, Yale University, New Haven, CT, USA.
John PachankisYale School of Public Health, Yale University, New Haven, CT, USA. Electronic address: john.pachankis@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
Developing Internet-Delivered, Mindfulness-based Intervention to Reduce HIV Risk and Promote Mental and Sexual Health among Young Adult MSMK23AT011173 · NCCIH · BROWN UNIVERSITY · PI SUN, SHUFANG · 2020 to 2024
$1.0M
Opportunities for suicide prevention integration into task-shifted mental health interventions in low-resourced contextsK01MH125142 · NIMH · YALE UNIVERSITY · PI HAGAMAN, ASHLEY K · 2021 to 2025
$964k
Developing efficient intervention technologies to reduce stigma-related stress, mental health problems, and HIV risk among young Chinese MSMR21TW011762 · FIC · YALE UNIVERSITY · PI LI, XIANHONG, PACHANKIS, JOHN EDWARD · 2020 to 2021
$437k
FIC NIH HHS R21 TW011762NCATS NIH HHS UL1 TR001863NCCIH NIH HHS K23 AT011173NIAID NIH HHS P30 AI042853NIMH NIH HHS K01 MH125142
6 · The paper itself

Abstract

objectiveLGBTQ-affirmative cognitive-behavioral therapy (CBT) addresses minority stress to improve sexual minority individuals' mental and behavioral health. This treatment has never been tested in high-stigma contexts like China using online delivery.

methodChinese young sexual minority men (n = 120; ages 16-30; HIV-negative; reporting depression and/or anxiety symptoms and past-90-day HIV-transmission-risk behavior), were randomized to receive 10 sessions of culturally adapted asynchronous LGBTQ-affirmative internet-based CBT (ICBT) or weekly assessments only. The primary outcome included HIV-transmission-risk behavior (i.e., past-30-day condomless anal sex). Secondary outcomes included HIV social-cognitive mechanisms (e.g., condom use self-efficacy), mental health (e.g., depression), and behavioral health (e.g., alcohol use), as well as minority stress (e.g., acceptance concerns), and universal (e.g., emotion regulation) mechanisms at baseline and 4- and 8-month follow-up. Moderation analyses examined treatment efficacy as a function of baseline stigma experiences and session completion.

resultsCompared to assessment only, LGBTQ-affirmative ICBT did not yield greater reductions in HIV-transmission-risk behavior or social-cognitive mechanisms. However, LGBTQ-affirmative ICBT yielded greater improvements in depression (d = -0.50, d = -0.63) and anxiety (d = -0.51, d = -0.49) at 4- and 8-month follow-up, respectively; alcohol use (d = -0.40) at 8-month follow-up; and certain minority stress (e.g., internalized stigma) and universal (i.e., emotion dysregulation) mechanisms compared to assessment only. LGBTQ-affirmative ICBT was more efficacious for reducing HIV-transmission-risk behavior for participants with lower internalized stigma (d = 0.42). Greater session completion predicted greater reductions in suicidality and rumination.

conclusionsLGBTQ-affirmative ICBT demonstrates preliminary efficacy for Chinese young sexual minority men. Findings can inform future interventions for young sexual minority men in contexts with limited affirmative supports.

Indexed as

Cognitive Behavioral TherapyHIV InfectionsInternet-Based InterventionSexual and Gender MinoritiesSocial StigmaAdolescentAdultChinaDepressionHumansInternetMaleRisk-TakingYoung AdultCognitive behavioral therapy (CBT)HIVMinority stressSexual and gender minoritiesSyndemic

Identifiers

PMID39029333
PMCPMC11371497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.