ArticleAnalytical chemistry2024
FragHub: A Mass Spectral Library Data Integration Workflow.
Article in Analytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Integrative physiological and metabolomic study of Hirschfeldia incana under short- and medium-term lead (Pb) stress.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- A Two-Layer Structural Key Framework for Linking Compound Identifiers and MS/MS Evidence in Spectral Database Curation.Metabolites · 2026Article
- Librarian: An Open-Access Web Application for High-Resolution Mass Spectral Library Assembly.Metabolites · 2026Article
- Molecular and physiological characterization of two sunflower near-isogenic lines with contrasting haplotypes for leaf senescence.BMC plant biology · 2026Article
- Exploiting predictive metabolomics of pearl millet phenotypic traits using untargeted profiling across a Brazilian germplasm panel.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Multiplexed LC-MS analysis reveals novel insights into grapevine defense mechanisms by expanding metabolome coverage.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- STRIKER: a spectral metadata repairing tool for expanding the comprehensiveness of spectral libraries.Journal of cheminformatics · 2026Article
- MassBank: an open and FAIR mass spectral data resource.Nucleic acids research · 2026Article
- Multi-omics uncovers nutrient stress-driven interactions in a syntheticISME communications · 2026Article
- Integrating metagenome-scale metabolic models and metabolomics to explore candidate biochemical interactions in cultivatedISME communications · 2026Article
- Metabolomic characterisation of traditional phytotherapeutic formulations used for snakebite envenomation treatment in Burkina Faso.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal.Cell genomics · 2025Article
- mineMS2: annotation of spectral libraries with exact fragmentation patterns.Journal of cheminformatics · 2025Article
- Graft union formation involves interactions among bud signals, carbon availability, dormancy release, wound responses and non-self-communication in grapevine.The Plant journal : for cell and molecular biology · 2025Article
- Introducing "Identification Probability" for Automated and Transferable Assessment of Metabolite Identification Confidence in Metabolomics and Related Studies.Analytical chemistry · 2025Review
- Introducing 'identification probability' for automated and transferable assessment of metabolite identification confidence in metabolomics and related studies.bioRxiv : the preprint server for biology · 2024Article
- Multi-Omics Unveils the Dual-Life of the Aquatic Plant Potamogeton nodosus.Physiologia plantarumArticle
- Fungal Pathogen Activity and Stress-Dependent Responses of Grapevine Wood to Esca and Drought.Physiologia plantarumArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Open mass spectral libraries (OMSLs) are critical for metabolite annotation and machine learning, especially given the rising volume of untargeted metabolomic studies and the development of annotation pipelines. Despite their importance, the practical application of OMSLs is hampered by the lack of standardized file formats, metadata fields, and supporting ontology. Current libraries, often restricted to specific topics or matrices, such as natural products, lipids, or the human metabolome, may limit the discovery potential of untargeted studies. The goal of FragHub is to provide users with the capability to integrate various OMSLs into a single unified format, thereby enhancing the annotation accuracy and reliability. FragHub addresses these challenges by integrating multiple OMSLs into a single comprehensive database, supporting various data formats, and harmonizing metadata. It also proposes some generic filters for the mass spectrum using a graphical user interface. Additionally, a workflow to generate in-house libraries compatible with FragHub is proposed. FragHub dynamically segregates libraries based on ionization modes and chromatography techniques, thereby enhancing data utility in metabolomic research. The FragHub Python code is publicly available under a MIT license, at the following repository: https://github.com/eMetaboHUB/FragHub. Generated data can be accessed at 10.5281/zenodo.11057687.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.