Evidence map›Paper›PMID 39028826›Full record

ArticleIslets2024

Decreased islet amyloid polypeptide staining in the islets of insulinoma patients.

Chisaki Ishibashi, Sho Yoneda, Yukari Fujita, Shingo Fujita, Kento Mitsushio, Harutoshi Ozawa, Megu Y Baden, Takao Nammo, Junji Kozawa, Hidetoshi Eguchi and 1 more

Abstract read
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In one paragraph

Article in Islets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chisaki IshibashiDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0003-4170-3661
Sho YonedaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Yukari FujitaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Shingo FujitaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Kento MitsushioDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Harutoshi OzawaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Megu Y BadenDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Takao NammoDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Junji KozawaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Hidetoshi EguchiDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Iichiro ShimomuraDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Islet amyloid polypeptide (IAPP) is a factor that regulates food intake and is secreted from both pancreatic islets and insulinoma cells. Here, we aimed to evaluate IAPP immunohistochemically in islets or insulinoma cells in association with clinical characteristics. We recruited six insulinoma patients and six body mass index-matched control patients with pancreatic diseases other than insulinoma whose glucose tolerance was confirmed to be normal preoperatively. IAPP and IAPP-insulin double staining were performed on pancreatic surgical specimens. We observed that the IAPP staining level and percentage of IAPP-positive beta cells tended to be lower (

Indexed as

InsulinomaIslet Amyloid PolypeptideIslets of LangerhansPancreatic NeoplasmsAdultAgedFemaleHumansImmunohistochemistryInsulinMaleMiddle AgedInsulinIslet Amyloid PolypeptideAmylinhypoglycemiaIAPPinsulinomaisletobesity

Identifiers

PMID39028826
PMCPMC11262209

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.