Evidence map›Paper›PMID 39028816›Full record

ArticleScience advances2024

Ultrastable piezoelectric biomaterial nanofibers and fabrics as an implantable and conformal electromechanical sensor patch.

Tong Li, Yongjiu Yuan, Long Gu, Jun Li, Yan Shao, Shan Yan, Yunhe Zhao, Corey Carlos, Yutao Dong, Hong Qian and 5 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Topologically Structured PLLA Fibers With Stress Concentration Effects for Health Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Designing the Next Generation of Biomaterials through Nanoengineering.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  18. Article
  19. Article
  20. Advanced Piezoelectric Materials, Devices, and Systems for Orthopedic Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tong LiDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-1045-4538
Yongjiu YuanDepartment of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0003-0473-1225
Long GuDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-7879-6086
Jun LiDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-7498-6736
Yan ShaoDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-8956-7721
Shan YanDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
Yunhe ZhaoDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-6147-3213
Corey CarlosDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
Yutao DongDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0003-3582-087X
Hong QianDepartment of Orthopedic, Nanjing Jinling Hospital, Nanjing 210002, China.ORCID 0009-0007-7563-973X
Xiong WangDepartment of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0002-7081-3248
Wenlong WuDepartment of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China.ORCID 0009-0001-4578-9880
Steven WangDepartment of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0001-8738-2889
Zuankai WangDepartment of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0002-3510-1122
Xudong WangDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-9762-6792

Funding

Nanogenerator-Driven Self-Sustainable Power Source for Intracardiac PacemakersR01HL157077 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, XUDONG · 2021 to 2024
$2.7M
Implantable Self-Powered Biofeedback Vagus Nerve Stimulator for Weight ControlR01EB034241 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI Xudong Wang · 2023 to 2026
$1.7M
NHLBI NIH HHS R01 HL157077NIBIB NIH HHS R01 EB034241
6 · The paper itself

Abstract

Poly(l-lactic acid) (PLLA) is a widely used U.S. Food and Drug Administration-approved implantable biomaterial that also possesses strong piezoelectricity. However, the intrinsically low stability of its high-energy piezoelectric β phase and random domain orientations associated with current synthesis approaches remain a critical roadblock to practical applications. Here, we report an interfacial anchoring strategy for fabricating core/shell PLLA/glycine (Gly) nanofibers (NFs) by electrospinning, which show a high ratio of piezoelectric β phase and excellent orientation alignment. The self-assembled core/shell structure offers strong intermolecular interactions between the -OH groups on Gly and C=O groups on PLLA, which promotes the crystallization of oriented PLLA polymer chains and stabilizes the β phase structure. As-received core/shell NFs exhibit substantially enhanced piezoelectric performance and excellent stability. An all NF-based nonwoven fabric is fabricated and assembled as a flexible nanogenerator. The device offers excellent conformality to heavily wrinkled surfaces and thus can precisely detect complex physiological motions often found from biological organs.

Indexed as

Biocompatible MaterialsNanofibersPolyestersGlycineProstheses and ImplantsTextilesBiocompatible MaterialsGlycinePolyesterspoly(lactide)

Identifiers

PMID39028816
PMCPMC11259165

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.