ArticleGeroScience2025
Body composition and aging: cross-sectional results from the INSPIRE study in people 20 to 93 years old.
Article in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Concurrent Training on Biomarkers, Morphological Variables, and Physical Performance in People with Sarcopenic Obesity: A Meta-Analysis with Meta-Regression.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Copeptin kinetics in healthy aging.The Journal of clinical endocrinology and metabolism · 2026Trial
- A 9-year longitudinal investigation into physiological aging in highly active older adults.GeroScience · 2026Article
- Body composition and aging among Tibetan adults living at high altitude: A cross-sectional study of 1,318 participants.The journal of nutrition, health & aging · 2026Article
- Biosociodemographic, Anthropometric, and Laboratory Profiles Associated with the Risk of Developing Chronic Kidney Disease Among Older Adults Living in Quilombola Communities: A Cross-sectional Study.Journal of immigrant and minority health · 2026Article
- Body composition in adults with phenylketonuria: A 5 years follow-up study.Molecular genetics and metabolism reports · 2026Article
- Advancing sarcopenia assessment with wearable and app-based technology: a scoping review.The journal of nutrition, health & aging · 2026Article
- Article
- National Reference Values of FFMI and FMI Using Body Composition Chart in Korean Adults.Nutrients · 2026Article
- Low Body Mass Index Increases Frailty Risk in Old-Old Adults: Findings From a 3-Year Longitudinal Study.Geriatrics & gerontology international · 2026Article
- Article
- Health-related effects of walking football in older adults: A real-world longitudinal study across a season comparing two age groups.PloS one · 2026Article
- A Systematic Review of Digital Health for Non-older Adults with Risk of Sarcopenia.Progress in rehabilitation medicine · 2026Review
- Age-Related Variations in Body Composition and Metabolic Health: A Cross-Sectional Study in Adults.Medicina (Kaunas, Lithuania) · 2025Article
- Beyond age: understanding how mindful eating and food label reading shape generational differences in health outcomes - a cross-sectional study.BMC public health · 2025Article
- Waist-Calf Circumference Ratio Is Associated with Body Composition, Physical Performance, and Muscle Strength in Older Women.Geriatrics (Basel, Switzerland) · 2025Article
- Biomarkers of aging: from molecules and surrogates to physiology and function.Physiological reviews · 2025Review
- Effects of Different Interventions Using Taekwondo, Boxing, and Elastic Band Training on Body Composition and Physical Function in Chilean Older Women: A Randomized Controlled Trial.Life (Basel, Switzerland) · 2025Article
- A deep learning sex-specific body composition ageing biomarker using dual-energy X-ray absorptiometry scan.Communications medicine · 2025Article
- Artificial Intelligence-Driven Biological Age Prediction Model Using Comprehensive Health Checkup Data: Development and Validation Study.JMIR aging · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Aging is characterized by several major changes, including altered body composition, which is associated with numerous negative clinical consequences such as sarcopenia, osteoporosis, and frailty. The study is to evaluate body composition parameters depending on age and sex in a population ranging from the young adult to the very old, and to identify break points in the association between body composition and age. In this cross-sectional study, we included the enrolment population of the French INSPIRE-T prospective cohort, accounting for 915 subjects (62% female). Age ranged from 20 to 93 years, median age (years) was 63 (IQR 27). Body composition (lean mass, fat mass, and bone mineral content) was assessed with dual-X-ray absorptiometry (DXA). Different break points in the relationship between age and body composition variables in males and females were identified using a segmented regression analysis adjusted on physical activity, nutritional status, educational level, and comorbidities. Lean mass decreased from the age of 55 years for males (CI 95% 44-66) and 31 years for females (CI 95% 23-39). For fat mass, we observed a trend towards an increase with age for males. For females, we observed an increase with age up to age 75 (CI 95% 62-86), followed by a decreasing trend. In this study, we described the relationship between body composition and age as a function of sex, establishing a foundation for further studies on predictive biomarkers of age-related body composition alteration.
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