Evidence map›Paper›PMID 39028178›Full record

ArticleJournal of clinical microbiology2024

Development and preliminary evaluation toward a new tuberculosis treatment monitoring tool: the PATHFAST TB LAM Ag assay.

Ayumi Akinaga, Masahito Takahashi, Takahito Yamazaki, Kinuyo Chikamatsu, Shuhei Matsushita, Yuichiro Hashimoto, Takako Iyoda, Takeshi Saika, Satoshi Mitarai

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ayumi Akinaga *PHC Corporation, Tokyo, Japan.ORCID 0009-0002-2569-2827
Masahito Takahashi *PHC Corporation, Tokyo, Japan.
Takahito YamazakiPHC Corporation, Tokyo, Japan.
Kinuyo ChikamatsuDepartment of Mycobacterium Reference and Research, The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Tokyo, Japan.
Shuhei MatsushitaPHC Corporation, Tokyo, Japan.ORCID 0009-0003-3782-664X
Yuichiro HashimotoPHC Corporation, Tokyo, Japan.ORCID 0009-0004-9788-7898
Takako IyodaLSI Medience Corporation, Tokyo, Japan.
Takeshi SaikaLSI Medience Corporation, Tokyo, Japan.
Satoshi MitaraiDepartment of Mycobacterium Reference and Research, The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Tokyo, Japan.ORCID 0000-0002-2288-077X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PATHFAST TB LAM Ag assay is based on a chemiluminescent enzyme immunoassay to quantify lipoarabinomannan (LAM) in sputum within 1 h, and was developed as an alternative to conventional culture methods for monitoring tuberculosis (TB) treatment. This study aimed to evaluate the analytical performance and initial clinical feasibility of using five

Indexed as

LipopolysaccharidesSensitivity and SpecificityAntigens, BacterialDrug MonitoringHumansImmunoenzyme TechniquesLuminescent MeasurementsMycobacterium tuberculosisReproducibility of ResultsSputumTuberculosisAntigens, BacteriallipoarabinomannanLipopolysaccharidesbacterial loadbiomarkerimmunoassaylipoarabinomannantuberculosis

Identifiers

PMID39028178
PMCPMC11323533

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.