Evidence map›Paper›PMID 39028131›Full record

ArticleThe world journal of men's health2025

Regenerative Therapy in Erectile Dysfunction: A Survey on Current Global Practice Trends and GAF Expert Recommendations.

Manaf Al Hashimi, Germar-M Pinggera, Taymour Mostafa, Amarnath Rambhatla, Taha Hamoda, Rupin Shah, Eric Chung, Ahmed Harraz, Mohamed Arafa, Tuncay Toprak and 38 more

Abstract read
In one paragraph

Article in The world journal of men's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Manaf Al HashimiDepartment of Urology, Burjeel Hospital, Abu Dhabi, UAE.ORCID https://orcid.org/0000-0002-2458-179X
Germar-M PinggeraGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-6463-2494
Taymour MostafaGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-3627-0662
Amarnath RambhatlaGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-1383-6670
Taha HamodaGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-8070-4088
Rupin ShahGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-7868-5949
Eric ChungGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-3373-3668
Ahmed HarrazGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-8902-517X
Mohamed ArafaGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0107-8857
Tuncay ToprakGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-1348-5273
Omer RaheemGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-6117-116X
Carlo GiulioniGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-9934-4011
Ponco BirowoGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-2934-6753
Luca BoeriGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0040-784X
Yassir JassimGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-8948-1338
Priyank KothariGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-3940-952X
Ranjit VishwakarmaGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-6784-2830
Bahadir SahinGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-4874-4178
Widi AtmokoGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-7793-7083
Safar GamidovGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-9128-2714
Cesar Rojas-CruzGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-3978-491X
Darren KatzGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0861-5643
Adriano FregonesiGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-6853-1014
Nazim GherabiGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-7364-047X
Armand ZiniGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-2194-5578
Christopher Chee Kong HoGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-8757-6867
Mohamed S Al-MarhoonGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-8397-1560
Marlon MartinezGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-1191-8154
Giorgio Ivan RussoGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-4687-7353
Ayman RashedGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-1994-2228
Gian Maria BusettoGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-7291-0316
Edmund KoGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-7465-3616
Hyun Jun ParkGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0566-9574
Selahittin CayanGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-4784-2208
Ramadan SalehGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0503-3533
Osvaldo RajmilGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-1987-9206
Dong Suk KimGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-7350-0303
Giovanni ColpiGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-1431-1777
Ryan SmithGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-3880-9740
Maged RagabGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-4790-3322
Ates KadiogluGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-4239-7638
Quang NguyenGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-1670-8885
Kadir BocuGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-4323-4037
Ahmed El-SakkaGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-8671-5952
Charalampos ThomasGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0139-2221
Hussain M AlnajjarGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-6364-0310
Hiva AlipourGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-8500-4208
Ashok AgarwalGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0585-1026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to examine current global practices in regenerative therapy (RT) for erectile dysfunction (ED) and to establish expert recommendations for its use, addressing the current lack of solid evidence and standardized guidelines. MATERIALS AND

methodsA 39-question survey was developed by senior Global Andrology Forum (GAF) experts to comprehensively cover clinical aspects of RT. This was distributed globally via a secure online Google Form to ED specialists through the GAF website, international professional societies, and social media, the responses were analyzed and presented for frequencies as percentages. Consensus on expert recommendations for RT use was achieved using the Delphi method.

resultsOut of 479 respondents from 62 countries, a third reported using RT for ED. The most popular treatment was low-intensity shock wave therapy (54.6%), followed by platelet-rich plasma (24.5%) and their combination (14.7%), with stem cell therapy being the least used (3.7%). The primary indication for RT was the refractory or adverse effects of PDE5 inhibitors, with the best effectiveness reported in middle-aged and mild-to-moderate ED patients. Respondents were confident about its overall safety, with a significant number expressing interest in RT's future use, despite pending guidelines support.

conclusionsThis inaugural global survey reveals a growing use of RT in ED treatment, showcasing its diverse clinical applications and potential for future widespread adoption. However, the lack of comprehensive evidence and clear guidelines requires further research to standardize RT practices in ED treatment.

Indexed as

Erectile dysfunctionExtracorporeal shockwave therapyPlatelet-rich plasmaRegenerative medicineStem cellsSurveys and questionnaires

Identifiers

PMID39028131
PMCPMC11937352

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.