Evidence map›Paper›PMID 39027513›Full record

ReviewHeliyon2024

Slow-release non-protein nitrogen sources in animal nutrition: A review.

Masoumeh Niazifar, Maghsoud Besharati, Muhammad Jabbar, Shakira Ghazanfar, Muhammad Asad, Valiollah Palangi, Hüseyin Eseceli, Maximilian Lackner

Abstract readReview
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The Effect ofBiology · 2026
    Article
  2. Article
  3. Review
  4. Effects of Substitution of Corn withAnimals : an open access journal from MDPI · 2026
    Article
  5. Article
  6. Article
  7. Slow-release urea, and propolis in dairy cow diets.Tropical animal health and production · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Masoumeh NiazifarDepartment of Animal Science, Ahar Faculty of Agriculture and Ntural Resources, University of Tabriz, Iran.
Maghsoud BesharatiDepartment of Animal Science, Ahar Faculty of Agriculture and Ntural Resources, University of Tabriz, Iran.
Muhammad JabbarFaculty of Biosciences, Department of Zoology, Cholistan University of Veterinary and Animal Sciences Bahawalpur, Pakistan.
Shakira GhazanfarNational Institute of Genomics and Advanced Biotechnology, Pakistan Agricultural Research Council Islamabad, Pakistan.
Muhammad AsadDepartment of Zoology, Division of Science and Technology, University of Education Lahore, Punjab, Pakistan.
Valiollah PalangiDepartment of Animal Science, Faculty of Agriculture, Ege University, 35100, Izmir, Turkiye.
Hüseyin EseceliDepartment of Nutrition Sciences, Faculty of Health Sciences, Bandirma Onyedi Eylul University, TR, 10200, Bandirma, Balikesir, Turkiye.
Maximilian LacknerDepartment of Industrial Engineering, University of Applied Sciences Technikum Wien, Hoechstaedtplatz 6, 1200, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today, feeding protein supply according to need in high-yielding lactating cows has become a big challenge. Protein is the most costly bulk constituent of animal diet, and the price of protein sources is increasing steadily, which is different from milk price rising. Therefore, one way for farmers to reduce feed costs is to reduce dietary protein share. Ruminants obtain their amino acids from 2 sources: amino acids from ruminally undegraded protein (RUP) and microbial protein synthesized in the rumen. A key goal in ruminant nutrition strategies, maximizing the use of rumen degradable protein (RDP), is through its efficient conversion into microbial protein. Urea is a supplement and a possible source of non-protein nitrogen (NPN) in ruminants' diets which meets bacteria's ammonia needs. Rumen ammonia sources include protein, peptides, amino acids, and other nitrogen-bearing compounds. As urea, uric acid, nitrate, and possibly nucleic acid are rapidly converted to ammonia, the ammonia reservoir indicates that the ruminal metabolism of ammonia is relatively small. Bacteria in the rumen can obtain between 40 and 95 percent of their nitrogen demand from ammonia, depending on their diet. Using NPN (non-protein nitrogen) as a reliable nitrogen source for ruminants was recognized over 100 years ago. Urea is quickly released in the rumen, its use in the diet is limited due to ammonia toxicity. So, the solution to this problem is that the product in nitrogen release rate from urea changes according to the digestion of fibers in the rumen. In the past, several slow-release products were made and evaluated. Slow-release urea (SRU) sources will also affect microbial growth and livestock performance compared to conventional plant protein sources. Acceptance of SRU sources, depending on their price compared to conventional plant protein ingredients is feasible. Studies has shown that the use of slow-release urea did not have a negative effect on digestibility, rumen parameters, milk production and livestock performance. Single-cell protein (SCP) is an emerging alternative protein source, currently being mainly studied for chicken and aquatic species.Finally, it is concluded that slow release urea can be used in feeding ruminants without any side effects.

Indexed as

BiuretNitrogenNon-protein nitrogen (NPN) sourcesProteinSCP (single cell protein)SRU (slow-release urea)

Identifiers

PMID39027513
PMCPMC11255499

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.