Evidence map›Paper›PMID 39027361›Full record

ArticleRegenerative biomaterials2024

Inhibition effect of copper-bearing metals on arterial neointimal hyperplasia via the AKT/Nrf2/ARE pathway

Peng Wang, Xiaohe Xu, Guisong Gu, Qianwen Guo, Yanzhi Rao, Ke Yang, Tong Xi, Yonghui Yuan, Shanshan Chen, Xun Qi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peng WangDepartment of Interventional Therapy, The First Hospital of China Medical University, Shenyang 110001, China.
Xiaohe XuDepartment of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Guisong GuShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China.
Qianwen GuoDepartment of Interventional Therapy, The First Hospital of China Medical University, Shenyang 110001, China.
Yanzhi RaoDepartment of Interventional Therapy, The First Hospital of China Medical University, Shenyang 110001, China.
Ke YangShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China.
Tong XiShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China.
Yonghui YuanLiaoning Cancer Hospital & Institute, Clinical Research Center for Malignant Tumor of Liaoning Province, Cancer Hospital of China Medical University, Shenyang 110042, China.
Shanshan ChenShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China.
Xun QiDepartment of Interventional Therapy, The First Hospital of China Medical University, Shenyang 110001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In-stent restenosis can be caused by the activation, proliferation and migration of vascular smooth muscle cells (VSMCs), which affects long-term efficacy of interventional therapy. Copper (Cu) has been proved to accelerate the endothelialization and reduce thrombosis formation, but little is known about its inhibition effect on the excessive proliferation of VSMCs. In this study, 316L-Cu stainless steel and L605-Cu cobalt-based alloy with varying Cu content were fabricated and their effects on surface property, blood compatibility and VSMCs were studied

Indexed as

AKT/Nrf2/ARE pathwaycopper-bearing metalneointimal hyperplasiastentvascular smooth muscle cells

Identifiers

PMID39027361
PMCPMC11256920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.