Evidence map›Paper›PMID 39027309›Full record

ArticleChemical science2024

α-Amino bicycloalkylation through organophotoredox catalysis.

Jeremy Nugent, Adrián López-Francés, Alistair J Sterling, Min Yi Tay, Nils Frank, James J Mousseau, Fernanda Duarte, Edward A Anderson

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Hetero[3.1.1]propellanes.Nature chemistry · 2026
    Article
  2. Cyclic Imine-BFSynlett : accounts and rapid communications in synthetic organic chemistry · 2025
    Article
  3. Photocatalytic Decarboxylative Alkylation of Cyclic Imine-BFJournal of the American Chemical Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeremy NugentDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK fernandaduartegonzalez@chem.ox.ac.uk edward.anderson@chem.ox.ac.uk.
Adrián López-FrancésDepartment of Organic Chemistry I, Faculty of Pharmacy and Lascaray Research Center, University of the Basque Country, UPV/EHU Paseo de la Universidad 7 01006 Vitoria-Gasteiz Spain.ORCID https://orcid.org/0000-0002-6363-2246
Alistair J SterlingDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK fernandaduartegonzalez@chem.ox.ac.uk edward.anderson@chem.ox.ac.uk.
Min Yi TayDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK fernandaduartegonzalez@chem.ox.ac.uk edward.anderson@chem.ox.ac.uk.
Nils FrankDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK fernandaduartegonzalez@chem.ox.ac.uk edward.anderson@chem.ox.ac.uk.
James J MousseauPfizer Worldwide Research and Development Eastern Point Road, Groton Connecticut 06340 USA.
Fernanda DuarteDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK fernandaduartegonzalez@chem.ox.ac.uk edward.anderson@chem.ox.ac.uk.ORCID https://orcid.org/0000-0002-6062-8209
Edward A AndersonDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK fernandaduartegonzalez@chem.ox.ac.uk edward.anderson@chem.ox.ac.uk.ORCID https://orcid.org/0000-0002-4149-0494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bridged bicycloalkanes such as bicyclo[1.1.1]pentanes (BCPs) and bicyclo[3.1.1]heptanes (BCHeps) are important motifs in contemporary drug design due to their potential to act as bioisosteres of disubstituted benzene rings, often resulting in compounds with improved physicochemical and pharmacokinetic properties. Access to such motifs with proximal nitrogen atoms (

Identifiers

PMID39027309
PMCPMC11253163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.