Evidence map›Paper›PMID 39027239›Full record

ArticleActa pharmaceutica Sinica. B2024

The clinical antiprotozoal drug nitazoxanide and its metabolite tizoxanide extend

Wenfeng Li, Shuming Chen, Jing Lang, Jing Luo, Jiahui Chen, Liping Zhang, Zhijie Sun, Deli Dong

Abstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Ethyl Acetate Extract ofCurrent issues in molecular biology · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenfeng LiDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
Shuming ChenDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
Jing LangDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
Jing LuoDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
Jiahui ChenDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
Liping ZhangDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
Zhijie SunDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
Deli DongDepartment of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The drugs extending healthspan in clinic have always been searched. Nitazoxanide is an FDA-approved clinical antiprotozoal drug. Nitazoxanide is rapidly metabolized to tizoxanide after absorption

Indexed as

AktAMPKC. elegansHealthspanLifespanMitochondrial uncouplingNitazoxanideTizoxanide

Identifiers

PMID39027239
PMCPMC11252460

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.