Evidence map›Paper›PMID 39027135›Full record

ArticleFrontiers in cellular and infection microbiology2024

Antimicrobial resistance genes harbored in invasive

Hyun Mi Kang, Kyung Ran Kim, Gahee Kim, Dong-Gun Lee, Yae Jean Kim, Eun Hwa Choi, Jina Lee, Ki Wook Yun

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Changing Genotypes andInfection & chemotherapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyun Mi KangDepartment of Pediatrics, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Kyung Ran KimDepartment of Pediatrics, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Gahee KimDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Dong-Gun LeeVaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Yae Jean KimDepartment of Pediatrics, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Eun Hwa ChoiDepartment of Pediatrics, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Jina Lee *Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Ki Wook Yun *Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: ACB complexes isolated from sterile body fluid of children in three referral hospitals were prospectively collected. Colistin susceptibility was additionally tested via broth microdilution. Whole genome sequencing was performed and antibiotic resistance genes were analyzed. Results: During January 2015 to December 2020, a total of 67 ACB complexes were isolated from sterile body fluid of children in three referral hospitals. The median age of the patients was 0.6 (interquartile range, 0.1-7.2) years old. Among all the isolates, 73.1% (n=49) were confirmed as AB and others as NB-ACB complex by whole genome sequencing. Among the AB isolates, only 22.4% susceptible to carbapenem. In particular, all clonal complex (CC) 92 AB (n=33) showed multi-drug resistance, whereas 31.3% in non-CC92 AB (n=16) (P<0.001). NB-ACB showed 100% susceptibility to all classes of antibiotics except 3rd generation cephalosporin (72.2%). The main mechanism of carbapenem resistance in AB was the Conclusions: In conclusion, monitoring and research for resistome in ACB complex is needed to identify and manage drug-resistant AB, particularly CC92 AB carrying the

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsMicrobial Sensitivity TestsWhole Genome SequencingAcinetobacter calcoaceticusbeta-LactamasesChildChild, PreschoolColistinCOVID-19Drug Resistance, BacterialDrug Resistance, Multiple, BacterialFemaleHumansInfantAnti-Bacterial Agentsbeta-LactamasesColistinAcinetobacter baumanniichildrencolistin resistancegenotyperesistome

Identifiers

PMID39027135
PMCPMC11254764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.