Evidence map›Paper›PMID 39026935›Full record

ArticleFrontiers in pediatrics2024

Infant with diffuse large B-cell lymphoma identified postmortem with homozygous founder Slavic

Tatiana P Volodashchik, Ekaterina A Polyakova, Taisia M Mikhaleuskaya, Inga S Sakovich, Aleksandra N Kupchinskaya, Aliaxandr Ch Dubrouski, Mikhail V Belevtsev, Joseph F Dasso, Dzmitry S Varabyou, Luigi D Notarangelo and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tatiana P VolodashchikResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Ekaterina A PolyakovaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Taisia M MikhaleuskayaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Inga S SakovichResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Aleksandra N KupchinskayaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Aliaxandr Ch DubrouskiPathological Unit, N.N. Alexandrov National Cancer Centre of Belarus, Lesnoy, Belarus.
Mikhail V BelevtsevResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Joseph F DassoDivision of Pediatric Allergy/Immunology, Johns Hopkins All Children's Hospital, Saint Petersburg, FL, United States.
Dzmitry S VarabyouDepartment of Geographical Ecology, Faculty of Geography and Geoinformatics, Belarusian State University, Minsk, Belarus.
Luigi D NotarangeloLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIH), Bethesda, MD, United States.
Jolan E WalterDivision of Pediatric Allergy/Immunology, Johns Hopkins All Children's Hospital, Saint Petersburg, FL, United States.
Svetlana O SharapovaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.

Funding

Mechanisms driving extrafollicular polyreactive B cell lineages in partial RAG deficiencyR01AI153830 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI WALTER, JOLAN ESZTER · 2021 to 2025
$2.2M
NIAID NIH HHS R01 AI153830
6 · The paper itself

Abstract

Background and aims: There is an increased risk of lymphomas in inborn errors of immunity (IEI); however, germline genetic testing is rarely used in oncological patients, even in those with early onset of cancer. Our study focuses on a child with a recombination-activating gene 1 ( Results: We identified one homozygous founder Conclusions: A targeted screening program designed to detect a Slavic founder variant in the

Indexed as

case reportinfantlymphomamalignancy in SCIDRAG deficiency

Identifiers

PMID39026935
PMCPMC11254792

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.