Evidence map›Paper›PMID 39026814›Full record

ArticlebioRxiv : the preprint server for biology2025

A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat.

Brian R Cornwell, Paige R Didier, Shannon E Grogans, Allegra S Anderson, Samiha Islam, Hyung Cho Kim, Manuel Kuhn, Rachael M Tillman, Juyoen Hur, Zachary S Scott and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Brian R CornwellDepartment of Psychological & Brain Sciences, George Washington University, Washington, DC 20006 USA.
Paige R DidierDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.
Shannon E GrogansDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.
Allegra S AndersonDepartment of Psychiatry and Human Behavior, Brown University, Providence, RI 02912 USA.
Samiha IslamDepartment of Psychology, University of Pennsylvania, Philadelphia, PA USA.
Hyung Cho KimDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.
Manuel KuhnCenter for Depression, Anxiety and Stress Research, McLean Hospital, Harvard Medical School, Belmont, MA 02478 USA.
Rachael M TillmanMcGill Neuropsychology, Bethesda, MD 20814 USA.
Juyoen HurDepartment of Psychology, Yonsei University, Seoul 03722, Republic of Korea.
Zachary S ScottDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.
Andrew S FoxDepartment of Psychology, University of California, Davis, CA 95616 USA.
Kathryn A DeYoungDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.
Jason F SmithDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.
Alexander J ShackmanDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.ORCID 0000-0002-3629-4704

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Engineered AAV Identification, Validation, and Dissemination Pipeline for Brain Cell Type-Specific Manipulation Across SpeciesUF1MH128336 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI FOX, ANDREW S, GRADINARU, VIVIANA · 2021 to 2021
$6.1M
Using Theory- and Data-Driven Neurocomputational Approaches and Digital Phenotyping to Understand RDoC Acute and Potential ThreatR01MH131264 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI ALEXANDER JOSEPH SHACKMAN · 2022 to 2026
$3.9M
Using Multimodal Neuroimaging and Real-World Experience Sampling to Understand Negative Affect and Paranoid Ideation in PsychosisR01MH121409 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI BLANCHARD, JACK J., SHACKMAN, ALEXANDER JOSEPH · 2020 to 2024
$3.7M
ORIGINS AND EMERGENCE OF MALADAPTIVE SOCIOEMOTIONAL BEHAVIOR DURING THE TRANSITION TO ADULTHOOD IN PRIMATESR01MH121735 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FOX, ANDREW S · 2020 to 2025
$3.6M
Prospective Determination of Neurobehavioral Risk for the Development of Emotion DisordersR01MH107444 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI SHACKMAN, ALEXANDER JOSEPH · 2016 to 2020
$3.4M
Using Computational Neuroimaging and Extended Smartphone Assessment to Understand the Pathways Linking Threat-Related Brain Circuits to Alcohol Misuse Across AdulthoodR01AA030042 · NIAAA · UNIV OF MARYLAND, COLLEGE PARK · PI ALEXANDER JOSEPH SHACKMAN · 2023 to 2026
$2.5M
Postdoctoral Training in Suicide ResearchT32MH126426 · NIMH · BROWN UNIVERSITY · PI IVAN W. MILLER, LAUREN M WEINSTOCK · 2021 to 2026
$1.8M
Explicit, Vicarious and Internalized Racial Discrimination on Daily Associations and Long-Term Health Trajectories among Filipino, Korean, and Indian AmericansR01AA031261 · NIAAA · UNIV OF MARYLAND, COLLEGE PARK · PI Derek K Iwamoto · 2024 to 2026
$1.7M
The Role of Anxiety-Related Brain Circuits in Tobacco Dependence and WithdrawalR21DA040717 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI SHACKMAN, ALEXANDER JOSEPH · 2016 to 2017
$418k
Rethinking the Neural Correlates of Uncertain Threat Anticipation with a Statistical Learning ApproachR21MH129851 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FOX, ANDREW S · 2022 to 2023
$414k
NIAAA NIH HHS R01 AA030042NIAAA NIH HHS R01 AA031261NIDA NIH HHS R21 DA040717NIH HHS P51 OD011107NIMH NIH HHS R01 MH107444NIMH NIH HHS R01 MH121409NIMH NIH HHS R01 MH121735NIMH NIH HHS R01 MH131264NIMH NIH HHS R21 MH129851NIMH NIH HHS T32 MH126426NIMH NIH HHS UF1 MH128336
6 · The paper itself

Abstract

Temporal dynamics play a central role in models of emotion:

Indexed as

bed nucleus of the stria terminalis (BST/BNST)central extended amygdala (EAc)fear and anxietyfMRIhuman affective neuroscienceResearch Domain Criteria (RDoC)

Identifiers

PMID39026814
PMCPMC11257510

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.