Evidence map›Paper›PMID 39026795›Full record

ArticlebioRxiv : the preprint server for biology2024

Repeated horizontal acquisition of lagriamide-producing symbionts in Lagriinae beetles.

Siddharth Uppal, Samantha C Waterworth, Alina Nick, Heiko Vogel, Laura V Flórez, Martin Kaltenpoth, Jason C Kwan

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Siddharth UppalDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, USA.ORCID 0000-0001-9604-6959
Samantha C WaterworthDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, USA.
Alina NickMax Planck Institute for Chemical Ecology, Jena, Germany.
Heiko VogelMax Planck Institute for Chemical Ecology, Jena, Germany.
Laura V FlórezDepartment of Plant and Environmental Science, University of Copenhagen, Copenhagen, Denmark.
Martin KaltenpothMax Planck Institute for Chemical Ecology, Jena, Germany.ORCID 0000-0001-9450-0345
Jason C KwanDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, USA.ORCID 0000-0001-9933-1536

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial symbionts associate with multicellular organisms on a continuum from facultative associations to mutual codependency. In some of the oldest intracellular symbioses there is exclusive vertical symbiont transmission, and co-diversification of symbiotic partners over millions of years. Such symbionts often undergo genome reduction due to low effective population sizes, frequent population bottlenecks, and reduced purifying selection. Here, we describe multiple independent acquisition events of closely related defensive symbionts followed by genome erosion in a group of Lagriinae beetles. Previous work in

Indexed as

biosynthetic gene clusterBurkholderiachemical defencelagriamideLagriinaemetagenomicssecondary metabolismsymbiont replacementsymbiosis

Identifiers

PMID39026795
PMCPMC11257431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.