Evidence map›Paper›PMID 39026742›Full record

ArticlebioRxiv : the preprint server for biology2025

GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis.

Joseph A Bisson, Miriam Gordillo, Ritu Kumar, Neranjan de Silva, Ellen Yang, Kelly M Banks, Zhong-Dong Shi, Kihyun Lee, Dapeng Yang, Wendy K Chung and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Joseph A BissonDepartment of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA.ORCID 0009-0006-3702-7882
Miriam GordilloDepartment of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA.
Ritu KumarDepartment of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA.
Neranjan de SilvaDepartment of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA.
Ellen YangDepartment of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA.
Kelly M BanksDepartment of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA.
Zhong-Dong ShiDevelopmental Biology Program, Sloan Kettering Institute, New York, NY, 10065, USA.
Kihyun LeeDevelopmental Biology Program, Sloan Kettering Institute, New York, NY, 10065, USA.
Dapeng YangDevelopmental Biology Program, Sloan Kettering Institute, New York, NY, 10065, USA.
Wendy K ChungChildrens Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Danwei HuangfuDevelopmental Biology Program, Sloan Kettering Institute, New York, NY, 10065, USA.ORCID 0000-0002-1145-6199
Todd EvansDepartment of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA.ORCID 0000-0002-7148-9849

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Weill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1M
THE DROSOPHILA GENETICS AND RNAI CORE (THE FLY CORE)P01HD068250 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, WENDY K, DONAHOE, PATRICIA K · 2011 to 2022
$17.1M
Weill Cornell/Rockefeller/Sloan Kettering MST ProgramT32GM152349 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KATHARINE C HSU · 2024 to 2026
$6.6M
A Gata456 Pipeline of DiscoveryR35HL135778 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI EVANS, TODD R · 2017 to 2023
$5.7M
Understanding Pancreatic Progenitors for Diabetes Cell-Replacement TherapyR01DK096239 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI HUANGFU, DANWEI · 2012 to 2021
$4.4M
Defining the downstream genetic networks regulated by GATA6 during human cardiogenesis using iPSC and hESC modelsF32HL152575 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI BISSON, JOSEPH A · 2020 to 2022
$212k
NCI NIH HHS P30 CA008748NHLBI NIH HHS F32 HL152575NHLBI NIH HHS R35 HL135778NICHD NIH HHS P01 HD068250NIDDK NIH HHS R01 DK096239NIGMS NIH HHS T32 GM007739NIGMS NIH HHS T32 GM152349
6 · The paper itself

Abstract

Haploinsufficiency for

Indexed as

cardiac progenitorscongenital heart diseaseeomesoderminheart development

Identifiers

PMID39026742
PMCPMC11257636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.