Evidence map›Paper›PMID 39026716›Full record

ArticlebioRxiv : the preprint server for biology2024

Antimicrobial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase.

Bright Obeng, Lucas J Bennett, Bailey E West, Dylan J Wagner, Patrick J Fleming, Morgan N Tasker, Madeleine K Lorenger, Dorothy R Smith, Tetiana Systuk, Sydni M Plummer and 7 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Bright Obeng
Lucas J Bennett
Bailey E West
Dylan J Wagner
Patrick J Fleming
Morgan N Tasker
Madeleine K Lorenger
Dorothy R Smith
Tetiana Systuk
Sydni M Plummer
Jeongwon Eom
Marissa D Paine
Collin T Frangos
Michael P Wilczek
Juyoung K Shim
Melissa S Maginnis
Julie A Gosse

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cetylpyridinium chloride (CPC) is a quaternary ammonium antimicrobial used in numerous personal care products, human food, cosmetic products, and cleaning solutions. Yet, there is minimal published data on CPC effects on eukaryotes, immune signaling, and human health. Previously, we showed that low-micromolar CPC inhibits rat mast cell function by inhibiting antigen (Ag)-stimulated Ca

Identifiers

PMID39026716
PMCPMC11257455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.