Evidence map›Paper›PMID 39026689›Full record

ArticlebioRxiv : the preprint server for biology2024

Sleep induced by mechanosensory stimulation provides cognitive and health benefits in

Sho Inami, Kyunghee Koh

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sho InamiDepartment of Neuroscience and the Farber Institute for Neurosciences, Thomas Jefferson University.
Kyunghee KohDepartment of Neuroscience and the Farber Institute for Neurosciences, Thomas Jefferson University.ORCID 0000-0003-0847-8204

Funding

Sexually-Dimorphic Regulation of SleepR01NS109151 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI KOH, KYUNGHEE · 2018 to 2022
$1.7M
Sleep induction by repetitive mechanosensory stimulation.R21NS130878 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI KOH, KYUNGHEE · 2022 to 2022
$429k
NINDS NIH HHS R01 NS109151NINDS NIH HHS R21 NS130878
6 · The paper itself

Abstract

Study Objectives: Sleep is a complex phenomenon regulated by various factors, including sensory input. Anecdotal observations have suggested that gentle rocking helps babies fall asleep, and experimental studies have verified that rocking promotes sleep in both humans and mice. Recent studies have expanded this understanding, demonstrating that gentle vibration also induces sleep in Methods: We administered gentle vibration to flies that slept very little due to a forced activation of wake-promoting neurons and investigated how the vibration influenced learning and memory in the courtship conditioning paradigm. Additionally, we examined the effects of VIS on synaptic downscaling by counting synapse numbers of select neurons. Finally, we determined whether vibration could induce sleep in Results: Vibration-induced sleep enhanced performance in a courtship conditioning paradigm and reduced the number of synapses in select neurons. Moreover, vibration improved sleep in Conclusions: Mechanosensory stimulation offers a promising non-invasive avenue for enhancing sleep, potentially providing associated cognitive and health benefits.

Identifiers

PMID39026689
PMCPMC11257551

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.