Evidence map›Paper›PMID 39026547›Full record

ArticleFrontiers in medicine2024

ReFerm

Olga Biskou, Susanna Walter, Hans Israelsen, Martin E Winberg, Olga Bednarska, Åsa V Keita

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05475314 (A Postbiotic Fermented Oat Gruel May Have a Beneficial Effect on the Colonic Mucosal Barrier in Patients With Irritable Bowel Syndrome), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05475314 nacompletednot on this map

A Postbiotic Fermented Oat Gruel May Have a Beneficial Effect on the Colonic Mucosal Barrier in Patients With Irritable Bowel Syndrome

TypeinterventionalSponsorNordisk Rebalance A/SRan2020 to 2022Enrolled30ConditionsIBS - Irritable Bowel SyndromeArmsReFerm(R)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olga BiskouDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Susanna WalterDepartment of Gastroenterology, Linköping University Hospital, Linköping, Sweden.
Hans IsraelsenNordic Rebalance A/S, Hillerød, Denmark.
Martin E WinbergDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Olga BednarskaDepartment of Gastroenterology, Linköping University Hospital, Linköping, Sweden.
Åsa V KeitaDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Irritable bowel syndrome (IBS) is a highly prevalent gastrointestinal disorder that affects ~4% of the global population. ReFerm Materials and methods: A total of 30 patients with moderate to severe IBS were treated with an enema containing ReFerm Results: Treatment with ReFerm Conclusion: ReFerm Clinical trial registration: https://clinicaltrials.gov, identifier: NCT05475314.

Indexed as

enteric nervous systemfunctional gastrointestinal disorderintestinal permeabilitymucosal immunologypostbiotics

Identifiers

PMID39026547
PMCPMC11255971

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.