Evidence map›Paper›PMID 39026457›Full record

SynthesisJournal of global health2024

Distribution of scoliosis in 2.22 million adolescents in mainland China: A population-wide analysis.

Shuai Xu, Kexin Li, Linyu Jin, Yanhui Dong, Yan Liang, Chenjun Liu, Peihan Wang, Zhuran Zhao, Yixuan Wang, Chen Guo and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shuai Xu *Department of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, China.
Kexin Li *Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.
Linyu Jin *Department of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, China.
Yanhui DongInstitute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China.
Yan LiangDepartment of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, China.
Chenjun LiuDepartment of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, China.
Peihan WangInstitute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.
Zhuran ZhaoDepartment of Paediatrics, Peking University People's Hospital, Peking University, Beijing, China.
Yixuan WangDepartment of Pain Medicine Centre, Peking University Third Hospital, Peking University, Beijing, China.
Chen GuoDepartment of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, China.
Zhenbo WangInstitute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.
Haiying LiuDepartment of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The characteristics of scoliosis afflicting school children and adolescents in mainland China are still unclear. Therefore, we conducted a systematic review to estimate scoliosis's prevalence and characterise its distribution in China. Methods: We screened PubMed, Scopus, WanFang, China National Knowledge Infrastructure, National Science and Technology Library, and WeiPu databases for mainland China articles published between 1 January 1980 and 31 October 2022. Among them, we identified population-wide scoliosis studies in school children and adolescents. The main outcomes were the positive rate of primary screening and the prevalence of final screening. Primary screening mainly included general examination with/without the forward bending test in school. The final screening entailed clinical diagnosis by Röntgen radiation in a hospital (based on primary screening). A meta-analysis of scoliosis distribution by gender was performed to calculate the odds ratios (ORs) and 95% confidence intervals (CIs). Further, we analysed the distributions of scoliosis by age, region, aetiological type, and severity of curvature, in addition to the correlation between its prevalence and altitude or latitude. Results: 77 studies with 2 224 320 participants were included. The positive rate through primary screening was 3.97%, whereas the prevalence of scoliosis at final screening was 1.20%. Analysing the data revealed a higher prevalence of scoliosis in girls (OR = 1.57; 95% CI = 1.38-1.81). The age-wise peak rate of scoliosis was 15-16 years (1.07%) in boys and 13-14 years (1.42%) in girls. The mean prevalence of scoliosis was 1.07% in the western region, 1.54% in the central, and 1.35% in the eastern. Scoliosis prevalence was not correlated with either altitude or latitude. The prevalence of idiopathic and congenital scoliosis was 1.18 and 0.03%. Among all subjects with scoliosis, 79.10 and 16.80% had mild and medium disease severity. Conclusions: According to this comprehensive study using data sets of scoliosis in adolescents across mainland China, the mean prevalence of scoliosis is 1.20%, yet 1.57 times higher in girls than boys, and is most prevalent in the middle region. Overall, scoliosis in adolescents could pose a burden to public health in mainland China. Registration: PROSPERO CRD42021231987.

Indexed as

ScoliosisAdolescentChinaFemaleHumansMalePrevalence

Identifiers

PMID39026457
PMCPMC11258535

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.