Evidence map›Paper›PMID 39026370›Full record

ArticleCritical care (London, England)2024

Early physical rehabilitation dosage in the intensive care unit associates with hospital outcomes after critical COVID-19.

Kirby P Mayer, Evan Haezebrouck, Lori M Ginoza, Clarisa Martinez, Minnie Jan, Lori A Michener, Lindsey E Fresenko, Ashley A Montgomery-Yates, Anna G Kalema, Amy M Pastva and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Kirby P MayerDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, 900 Rose Street, Lexington, KY, 40536, USA. Kpmaye2@uky.edu.
Evan HaezebrouckUniversity of Michigan Hospital, University of Michigan Health, Ann Arbor, MI, USA.
Lori M GinozaDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Clarisa MartinezDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Minnie JanDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Lori A MichenerDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Lindsey E FresenkoDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, 900 Rose Street, Lexington, KY, 40536, USA.
Ashley A Montgomery-YatesDepartment of Internal Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.
Anna G KalemaDepartment of Internal Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.
Amy M PastvaDivision of Physical Therapy, Duke University School of Medicine, Durham, NC, USA.
Michelle BiehlDepartment of Physical Medicine and Rehabilitation, Cleveland Clinic, Cleveland, OH, USA.
Matthew F Mart *Division of Allergy, Pulmonary, and Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA.
Joshua K Johnson *Division of Physical Therapy, Duke University School of Medicine, Durham, NC, USA.

Funding

Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
NRSA Training CoreTL1TR001997 · NCATS · UNIVERSITY OF KENTUCKY · PI PENDERGAST, JULIE S, STOOPS, WILLIAM WALTON · 2016 to 2025
$4.2M
Cellular and Physical Function Outcomes Leading to Failed Muscle Recovery After Critical IllnessK23AR079583 · NIAMS · UNIVERSITY OF KENTUCKY · PI Kirby P Mayer · 2022 to 2026
$744k
The Role of Mitochondrial Dysfunction in Physical Recovery after Critical IllnessIK2RX004799 · VA · VETERANS HEALTH ADMINISTRATION · PI Matthew Franklin Mart · 2024 to 2026
–
NCATS NIH HHS KL2 TR002245NCATS NIH HHS TL1 TR001997NIAMS NIH HHS K23 AR079583NIAMS NIH HHS K23AR079583NIMHD NIH HHS L32 MD017732RRD VA IK2 RX004799
6 · The paper itself

Abstract

objectiveTo examine the relationship between physical rehabilitation parameters including an approach to quantifying dosage with hospital outcomes for patients with critical COVID-19.

designRetrospective practice analysis from March 5, 2020, to April 15, 2021.

settingIntensive care units (ICU) at four medical institutions. PATIENTS: n = 3780 adults with ICU admission and diagnosis of COVID-19.

interventionsWe measured the physical rehabilitation treatment delivered in ICU and patient outcomes: (1) mortality; (2) discharge disposition; and (3) physical function at hospital discharge measured by the Activity Measure-Post Acute Care (AM-PAC) "6-Clicks" (6-24, 24 = greater functional independence). Physical rehabilitation dosage was defined as the average mobility level scores in the first three sessions (a surrogate measure of intensity) multiplied by the rehabilitation frequency (PT + OT frequency in hospital). MEASUREMENTS AND MAIN

resultsThe cohort was a mean 64 ± 16 years old, 41% female, mean BMI of 32 ± 9 kg/m

conclusionsGreater physical rehabilitation exposure early in the ICU is associated with better physical function at hospital discharge.

Indexed as

COVID-19Intensive Care UnitsAgedCritical IllnessFemaleHumansMaleMiddle AgedPatient DischargeRetrospective StudiesCOVIDCritical illnessEarly mobilizationOccupational therapyPhysical rehabilitationPhysical therapy

Identifiers

PMID39026370
PMCPMC11256579

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.