Evidence map›Paper›PMID 39026178›Full record

ArticleBMC musculoskeletal disorders2024

3D-printed porous titanium suture anchor: a rabbit lateral femoral condyle model.

Lien-Chen Wu, Yueh-Ying Hsieh, Ting-Shuo Hsu, Po-Yi Liu, Fon-Yih Tsuang, Yi-Jie Kuo, Chia-Hsien Chen, Tin Van Huynh, Chang-Jung Chiang

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lien-Chen WuDepartment of Orthopaedics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan.
Yueh-Ying HsiehDepartment of Orthopaedics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan.
Ting-Shuo HsuDepartment of Orthopaedics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan.
Po-Yi LiuDepartment of Orthopaedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Fon-Yih TsuangDivision of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei City, 10022, Taiwan.
Yi-Jie KuoDepartment of Orthopaedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Chia-Hsien ChenDepartment of Orthopaedics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan.
Tin Van HuynhDepartment of Interventional Cardiology, Thong Nhat Hospital, Ho Chi Minh City, Vietnam.
Chang-Jung ChiangDepartment of Orthopaedics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan. cjchiang@s.tmu.edu.tw.

Funding

National Science and Technology Council (NSTC), Taiwan NSTC 111-2622-B-038-006
6 · The paper itself

Abstract

backgroundThe inclusion of a connecting path in a porous implant can promote nutrient diffusion to cells and enhance bone ingrowth. Consequently, this study aimed to evaluate the biomechanical, radiographic, and histopathological performance of a novel 3D-printed porous suture anchor in a rabbit femur model.

methodsThree test groups were formed based on the type of suture anchor (SA): Commercial SA (CSA, Group A, n = 20), custom solid SA (CSSA, Group B, n = 20), and custom porous SA (CPSA, Group C, n = 20). The SAs were implanted in the lateral femoral condyle of the right leg in each rabbit. The rabbits (New Zealand white rabbits, male, mean body weight of 2.8 ± 0.5 kg, age 8 months) underwent identical treatment and were randomized into experimental and control groups via computer-generated randomization. Five rabbits (10 femoral condyles) were euthanized at 0, 4, 8, and 12 weeks post-implantation for micro-CT, histological analysis, and biomechanical testing.

resultsAt 12 weeks, the CPSA showed a higher BV/TV (median 0.7301, IQR 0.7276-0.7315) than the CSSA and CSA. The histological analysis showed mineralized osteocytes near the SA. At 4 weeks, new bone was observed around the CPSA and had penetrated its porous structure. By 12 weeks, there was no significant difference in ultimate failure load between the CSA and CPSA.

conclusionsWe demonstrated that the innovative 3D-printed porous suture anchor exhibited comparable pullout strength to conventional threaded suture anchors at the 12-week postoperative time-point period. Furthermore, our porous anchor design enhanced new bone formation and facilitated bone growth into the implant structure, resulting in improved biomechanical stability.

Indexed as

FemurPrinting, Three-DimensionalSuture AnchorsTitaniumAnimalsBiomechanical PhenomenaMalePorosityRabbitsX-Ray MicrotomographyTitanium3D-printed porous anchorBone formationBone ingrowthSuture anchor

Identifiers

PMID39026178
PMCPMC11256369

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.