Evidence map›Paper›PMID 39026158›Full record

ArticleInternational journal of emergency medicine2024

Catecholamine concentration as a predictor of mortality in emergency surgical patients.

João Isuk Suh, Daiane Leite da Roza, Filipe Matheus Cadamuro, Luiz Marcelo Sá Malbouisson, Talita Rojas Sanches, Lúcia Andrade

Abstract read
In one paragraph

Article in International journal of emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

João Isuk SuhNephrology Division, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Daiane Leite da RozaDepartment of Epidemiology, School of Public Health, University of São Paulo, São Paulo, Brazil.
Filipe Matheus CadamuroTrauma Intensive Care Unit, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Luiz Marcelo Sá MalbouissonTrauma Intensive Care Unit, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Talita Rojas SanchesNephrology Division, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Lúcia AndradeNephrology Division, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil. lucia.andrade@fm.usp.br.

Funding

Brazilian Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, National Council for Scientific and Technological 309683/2021-1
6 · The paper itself

Abstract

backgroundTrauma and emergency surgery are major causes of morbidity and mortality. The objective of this study was to determine whether serum levels of epinephrine and norepinephrine are associated with aging and mortality.

methodsThis was a prospective observational cohort study conducted in a surgical critical care unit. We included 90 patients who were admitted for postoperative care, because of major trauma, or both. We collected demographic and clinical variables, as well as serum levels of epinephrine and norepinephrine.

resultsFor patients in the > 60-year age group, the use of vasoactive drugs was found to be associated with an undetectable epinephrine level (OR [95% CI] = 6.36 [1.12, 36.08]), p = 0.05). For the patients with undetectable epinephrine levels, the in-hospital mortality was higher among those with a norepinephrine level ≥ 2006.5 pg/mL (OR [95% CI] = 4.00 [1.27, 12.58]), p = 0.03).

conclusionsThere is an association between age and mortality. Undetectable serum epinephrine, which is more common in older patients, could contribute to poor outcomes. The use of epinephrine might improve the clinical prognosis in older surgical patients with shock.

Indexed as

EpinephrineICU outcomeMortalityNorepinephrineSAPSSOFAVasopressors

Identifiers

PMID39026158
PMCPMC11264696

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.