Evidence map›Paper›PMID 39025999›Full record

ArticleScientific reports2024

Down syndrome and postoperative hemodynamics in patients undergoing surgery for congenital cardiac communications.

Eloisa Sassá Carvalho, Juliano Gomes Penha, Nair Yukie Maeda, Kelly Cristina O Abud, Maria Francilene S Souza, Claudia R P Castro, Johnny X Dos Santos, Juliana Pereira, Antonio Augusto Lopes

Abstract read
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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eloisa Sassá CarvalhoHeart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Juliano Gomes PenhaHeart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Nair Yukie MaedaPró-Sangue Foundation, São Paulo, Brazil.
Kelly Cristina O AbudHeart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Maria Francilene S SouzaHeart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Claudia R P CastroHeart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Johnny X Dos SantosHeart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Juliana PereiraLaboratory of Medical Investigation On Pathogenesis and Targeted Therapy in Onco-Immuno-Hematology (LIM-31), University of São Paulo, São Paulo, Brazil.
Antonio Augusto LopesHeart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil. aablopes@usp.br.

Funding

FAPESP - Foundation for Research Support of the State of São Paulo, São Paulo, Brazil Grants #2015/21587-5 and #2019/18789-5.
6 · The paper itself

Abstract

Although Down syndrome (DS) is considered a risk factor for hemodynamic instabilities (mainly pulmonary hypertension-PH) following surgery for congenital cardiac communications, many DS patients do surprising well postoperatively. We prospectively analyzed perioperative factors for a possible correlation with post-cardiopulmonary bypass (CPB) inflammatory reaction and postoperative PH in pediatric subjects. Sixty patients were enrolled (age 3 to 35 months), 39 of them with DS. Clinical and echocardiographic parameters (anatomical and hemodynamic) were computed preoperatively. Pulmonary and systemic mean arterial pressures (PAP and SAP) were assessed invasively intra and postoperatively. Immediate postoperative PAP/SAP ratio (PAP/SAP

Indexed as

Down SyndromeHeart Defects, CongenitalHemodynamicsCardiopulmonary BypassChild, PreschoolFemaleHumansHypertension, PulmonaryInfantMalePostoperative ComplicationsPostoperative PeriodProspective StudiesRisk FactorsCongenital heart diseasesDown syndromeInflammatory mediatorsPediatric cardiac surgeryPostoperative intensive carePulmonary hypertension

Identifiers

PMID39025999
PMCPMC11258288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.